Treatment of Neuropsychiatric Lupus
Directly targets autoimmune antibodies that cause lupus-related seizures and cognitive impairment. Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder with poorly understood etiology and no significantly effective treatment. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million...
Published: 4/1/2025
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Inventor(s): Henri Tiedge, Ilham Muslimov, Ellen Ginzler
Keywords(s): lupus, regulatory RNAs, seizures, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Therapeutics and Vaccines
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Chip-scale Photonic Processing Neuroprosthetic Detector
A novel technology for optimizing visual prosthetics for individuals with foveal blindness.
Background:
The International Agency for the Prevention of Blindness expects 196 million people to suffer from macular degeneration worldwide in 2020. Millions more will suffer from traumatic ocular injury or glaucoma or other foveal defects. The result will...
Published: 4/1/2025
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Inventor(s): Stephen Macknik, Susana Martinez-Conde, Satyavolu Papa Rao, Spyridon Galis, John Carter, Olivya Caballero
Keywords(s): brain, cortex, multi-color spatiochromatic encoding, neural recording, OBServ, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare, Technology Classifications > Medical Devices, Campus > NY CREATES, Campus > SUNY Polytechnic Institute
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Opioid Tolerance-Abating Treatment
A precision medicine approach blocking formation of analgesic tolerance and reversing analgesic tolerance from chronic opioid administration.
Background
Opiates are commonly prescribed in the US for surgical and other severe pain; and many people also obtain opioids illegally. Opioids work well for acute pain; but for those with chronic pain requiring...
Published: 4/1/2025
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Inventor(s): Alan Gintzler, Nai-Jiang Liu
Keywords(s): Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > SUNY Downstate Health Sciences University
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Use of 2-Hydroxyoleic Acid for the Treatment of Systemic Lupus Erythematosus and Other Immune Pathologies
A novel B cell tolerance pathway activated by the lipid enzyme sphingomyelin synthases 2 (SMS2).
Background:
Autoimmune diseases such as Systemic Lupus Erythematosus are chronic, painful and debilitating. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have some form of lupus. The...
Published: 4/1/2025
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Inventor(s): Chongmin Huan, Christopher Roman, Peiqi Ou
Keywords(s): TAF, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Therapeutics and Vaccines
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Novel, Reliable and Rapid Diagnostic Test for TBI
An effective, reliable and rapid diagnostic test to determine traumatic brain injury with the aid of a laptop. Background: Mild traumatic brain injury (TBI) is often followed by acute cognitive impairments. These differ in type, severity and persistence. Most patients recover, but about 20% progress to post-concussive syndrome (PCS), and a long-lasting...
Published: 4/1/2025
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Inventor(s): Peter Bergold, William Lytton, Yosef Skolnick
Keywords(s): cerebral hemisphere, crossed and uncrossed reaction time, reaction speed, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Diagnostics
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Autonomous Brain Machine Interface
An advanced system that enables patients to better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 4/1/2025
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Inventor(s): Joseph Francis, Venkata S. Aditya Tarigoppula, Brandi Marsh
Keywords(s):
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Computers
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Intramedullary Temporomandibular Joint (TMJ) Implant
A novel TMJ implant that reduces stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 4/1/2025
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Inventor(s): Martin Pendola
Keywords(s):
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Medical Devices
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Cancer Blood Testing Using BC200 RNA Isolated from Peripherial Blood for Diagnosis and Treatment of Invasive Breast Cancer
Kits can be developed to facilitate the isolation and characterization of circulating tumor cells expressing these breast cancer small RNAs. Background: Breast cancer remains a leading cause of death from malignancies in women, despite the fact that early detection via mammography and improved therapeutic intervention have resulted in a decrease of...
Published: 4/1/2025
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Inventor(s): Henri Tiedge, Anna Iacoangeli
Keywords(s): TAF, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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KIBRA-PKMzeta Interactions in LTP and Memory Maintenance
This technology offers the potential for developing novel and effective treatments for mood- and memory-related disorders and neuropathic pain.
Background:
During learning, neurons produce an enzyme called protein kinase M zeta (PKMzeta) which is responsible for (1) maintaining newly strengthened connections between neurons, and (2) memory. PKMzeta...
Published: 4/1/2025
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Inventor(s): Todd Sacktor
Keywords(s): gene therapy, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Vasocure
https://vasocuretherapeutics.com/
https://vasocuretherapeutics.com/
https://suny.technologypublisher.com/files/sites/vasocure_transparenr1.png
https://suny.technologypublisher.com/files/sites/vasocure_transparenr1.png
Published: 4/1/2025
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Inventor(s):
Keywords(s): Startups
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > SUNY Downstate Health Sciences University
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