Targeting the Folding of Hsp90 Clients by Predicting Their Local Unfolding Status
Computationally predicts potential ideal interaction points for the molecular chaperone heat shock protein-90 (Hsp90).
Background:
Molecular chaperones assist in the folding of unfolded and misfolded polypeptides by stabilization of folding intermediates and prevention of protein misfolding and aggregation. Molecular chaperones are present in all...
Published: 7/11/2023
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Inventor(s): Mehdi Mollapour, Mark Woodford, Gennady Bratslavsky, Dimitra Bourboulia
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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