CMT-3 nanoformulations for systemic and local administration for inflammation control
The technology introduces innovative telodendrimer nanoformulations of the anti-inflammatory agent CMT-3 that enhance its solubility and bioavailability for effective systemic and local inflammation control.
Background:
CMT-3 is a potent anti-inflammatory compound with promising therapeutic potential; however, its poor water solubility significantly...
Published: 6/22/2026
|
Inventor(s): Juntao Luo, Robert Cooney, Qinghe Meng, Xiaojing Wang, Dandan Guo, Gary Nieman
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
|
Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness.
Background:
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026
|
Inventor(s): Yamin Li, Yuqin Men, Qinghe Meng, Robert Cooney
Keywords(s): anti-inflammatory therapeutic, drug delivery, lipids, mRNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
|
Lipid nanoparticles for targeted delivery of therapeutic agents in acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver a combination of anti-inflammatory and immune-modulating drugs directly to the lungs, offering a more effective and targeted treatment for acute lung injury and acute respiratory distress syndrome.
Background:
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)...
Published: 4/2/2026
|
Inventor(s): Yamin Li, Yuqin Men, Robert Cooney, Qinghe Meng
Keywords(s): acute lung injury, anti-inflammatory therapeutic, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
|