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Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care

A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background: Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 12/11/2023   |   Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines

High-Yield, High-Stability Overexpression Tag for Bacterial Protein Production

A novel protein purification tag achieves high yields of pure, soluble, full-length recombinant proteins Background: Current protein purification methods rely on solubility-enhancing tags that permit purification with affinity chromatography and subsequent cleavage with specific proteases to extract the target proteins. Researchers have now developed...
Published: 7/11/2023   |   Inventor(s): Stewart Loh, Jeung-hoi Ha
Keywords(s): TAF, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Research Tools and Reagents

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