Bruton's Tyrosine Kinase as Anti-Cancer Drug Target
This technology identifies Bruton's Tyrosine Kinase (BTK) as a novel target in breast cancer therapy and provides methods for treatment and diagnosis by inhibiting a specific BTK variant.
Background:
Protein tyrosine kinases (PTKs) are essential enzymes involved in cellular communication and regulation, often playing a significant role in cancer...
Published: 5/5/2026
|
Inventor(s): Douglas Conklin, Antonis Kourtidis, Cheryl Eifert
Keywords(s): breast cancer, cancer, TAF, Technologies, therapeutic targets
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
|
Peptide Therapeutic Against HIV
This technology presents a computationally evolved peptide therapeutic that targets human lysine tRNA to disrupt the HIV-1 replication cycle.
Background:
HIV-1 replication poses a significant challenge for therapeutic intervention due to the virus’s complex interaction with host cellular mechanisms. Existing treatments often face limitations...
Published: 3/27/2026
|
Inventor(s): Paul Agris, Carol Hall, Xingqing Xiao
Keywords(s): HIV/AIDS, therapeutic targets
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Albany
|
Suppression of Therapeutic Escape in Breast Cancer by BTK Inhibition
This technology offers the potential of new and novel cancer treatments based on various inhibitors of protein tyrosine kinases
Background:
Genes that regulate extracellular growth, differentiation, and developmental signals are commonly mutated in cancers. Protein tyrosine kinases (PTKs) mediate the reversible process of tyrosine phosphorylation,...
Published: 4/9/2026
|
Inventor(s): Douglas Conklin, Xianhui Wang
Keywords(s): breast cancer, cancer, Technologies, therapeutic targets
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Therapeutics and Vaccines
|