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Targeting Alternative N-terminal Kinases

Offers the potential of treating epithelial tumors with therapeutics based on BTK-C, a palmitoylated isoform of Bruton’s tyrosine kinase (BTK). Background: Bruton’s tyrosine kinase (BTK) plays an active role in the development, maturation, and signaling of B cells. BTK regulates cell proliferation, survival, and migration in various...
Published: 3/12/2024   |   Inventor(s): Douglas Conklin, Mostafa Kokabee, Xianhui Wang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents

A Novel PET Imaging Agent for Diagnosing Bacterial Infections

A PET tracer, [18F]F-PABA which is taken up only by bacterial cells thus making it specific for diagnosing infection. Background: Bacterial infections such as those of prosthetic joints, bones (osteomyelitis) and heart valves (infective endocarditis) are difficult to diagnose and treat, and are a major cause of mortality, morbidity and health care...
Published: 2/28/2024   |   Inventor(s): Peter Tonge, Zhuo Zhang, Peter Smith-Jones, Hui Wang, Li Liu
Keywords(s): Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Diagnostics, Technology Classifications > Research Tools and Reagents

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