Production of Salivary Gland Epithelial Progenitors and Acinar Organoids
Human UPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function.
Background:
Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 3/8/2024
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Inventor(s): Stelios Andreadis, Ronel Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Featured, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays
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Drill Guide/Suture Passer for Posterior Approach Total Hip Soft Tissue Repair
Combined drill guide and suture passer for use in assisting repair following posterior approach total hip arthroplasty.
Background:
The posterior approach to the hip for total hip replacement as well as trauma, pediatric orthopedic surgery, and tumors is the most common approach for total hip arthroplasties. However, the performance of this...
Published: 12/26/2023
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Inventor(s): Timothy Damron
Keywords(s): biomedical engineering, biotechnology, hardware, healthcare, medical devices, medical equipment, orthopedics, surgery, suturing technique, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices
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DsDNA-templated Substrates as Fluorescent Probes for CRISPR-Cas12a-based Diagnostics
New design for CRISPR-based fluorescent probes improves disease diagnostics and sensing. Background: Scientists use the naturally occurring CRISPR-Cas12a gene editing system as a valuable tool for disease diagnostics. When Cas12a finds its target -- a sequence of double-stranded DNA -- it cuts it. In the process, it also cuts other nearby DNAs. Scientists...
Published: 1/22/2024
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Inventor(s): Mehmet Yigit, Christopher Smith
Keywords(s): agriculture, biotechnology, Cas12a, Cas12a, CRISPR, CRISPR, detection, detection, DNA, DNA, fluorescence, fluorescence, RNA, RNA, sensor, sensor
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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