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Biomarker Diagnostic for Crohn's Disease Severity

There are approximately 1.8 million people suffering from Crohn's disease in the US and Europe. A portion of these will require aggressive treatment, such as surgical resections and biologics. Upstate has identified a novel mutant fusion mRNA that allows easy and definitive identification of a subset of Crohn's Disease patients that is highly...
Published: 9/17/2020   |   Inventor(s): William Kerr, Frank Middleton, Sandra Denney
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University

Saliva MicroRNA-Based Diagnosis of Children With Autism

A panel of 14 miRNA biomarkers in saliva that are 91% accurate in diagnosing autism in children aged 4-13 (both the false positive and false negative rates are less than 10%). Analysis of the saliva sample can be done using next generation sequencing or qPCR. Because the current gold standard autism spectrum disorder diagnostic is a questionaire which...
Published: 10/24/2019   |   Inventor(s): Steven Hicks, Frank Middleton
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays

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