Lung Inflation for Upper Airway Obstruction Emergencies
A mobile, easy-to-use device that provides quick emergency support to patients suffering from obstructive apnea.
Background:
Epileptic seizures can cause laryngospasm, leading to complete obstructive apnea. During periods of obstructive apnea, cardiac rhythm changes indicative of hypoxia occur within tens of seconds. Additionally, when the laryngospasm...
Published: 6/21/2024
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Inventor(s): Mark Stewart, Richard Kollmar, Krishnamurthi Sundaram, Joshua Silverman, Ko Nakase, Hamid Arjomandi
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Medical Devices, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use
" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are diagnosed...
Published: 1/22/2024
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Inventor(s): Li Niu, Zhen Huang
Keywords(s): Technologies
Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Campus, Campus > University at Albany
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Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's.
Background:
Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 9/26/2024
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Inventor(s): Li Niu, Zhen Huang, Yan Han, Congzhou Wang, Jae Seon Park
Keywords(s): RNA, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus, Campus > University at Albany
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Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 1/29/2024
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Inventor(s): Li Niu, Zhen Huang
Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
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RNA Hydrogel
Created from an RNA with unique sequence through self-assembly, this hydrogel has potential in a range of medical and research applications RSS.HDBackground> Background: < Hydrogels are water-saturated turgid materials used for a wide range of applications such as tissue engineering scaffolds and drug delivery vehicles. Hydrogels are one of...
Published: 5/1/2024
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Inventor(s): Li Niu, Zhen Huang
Keywords(s): Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
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Hydrophobic Sponges for Oil
An oil recovery sponge with a natural absorbent substrate that is reusable up to 20 times, making it ideal for responding to oil spills Background: Oil recovery systems that use a sponge to soak up the contaminated oil may be reused and then may be disposed of because they become less efficient with subsequent re-use. Technology Overview: Researchers...
Published: 9/6/2024
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Inventor(s): Benjamin Chu, Benjamin Hsiao, Zhe Wang
Keywords(s): 3-dimensional pores, Hydrophobic porous materials, oil removal, Technologies
Category(s): Campus > Stony Brook University, Technology Classifications > Environment
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Porous Graphene Based Composite Membranes for Nanofiltration, Desalination and Pervaporation
An ultra-thin barrier from a single atomic layer of graphene-based materials with adjustable pore size Background: For membrane separation technology, preparing a very thin barrier layer with high selectivity, high throughput, low fouling, and long lasting properties forms the ultimate set of goals, which the widely used polymeric materials...
Published: 8/27/2024
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Inventor(s): Benjamin Chu, Benjamin Hsiao, Hongyang Ma, Zhe Wang
Keywords(s): chemically cross-linking, desalination, electrospun scaffold, membrane, nanofiltration, pervaporation, Porous graphene oxide, Technologies, water channels
Category(s): Campus > Stony Brook University, Technology Classifications > Education and Training, Technology Classifications > Drug Delivery, Technology Classifications > Medical Devices
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Spinal Restoration through Bio-Congruent Implantable Cobot Devices
Combining robotic engineering, biology, and computer science to bring revolutionary advances in the field of spinal restoration Background: Back pain and spine related discomforts are the leading cause of trips to the doctor and ER. The design of the spine is extremely complex and unique so if any component of its anatomy fails, it is very difficult...
Published: 3/23/2023
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Inventor(s): Daniel Birk, David Rubenstein, Qiaode Ge, IV Ramakrishnan, T Venkatesh, Nilanjan Chakraburty
Keywords(s):
Category(s): Campus > Stony Brook University, Technology Classifications > Medical Devices
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Knowledge Discovery from Citation Networks
A Bernoulli Process Topic (BPT) model that enables knowledge discovery from citation networks to improve data mining tasks
Background:
Knowledge discovery from citation networks (i.e., textual data with links such as scientific articles, legal documents, webpages, and emails) provides insight into vast areas since huge repositories are made available...
Published: 4/18/2024
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Inventor(s): Zhongfei Zhang, Zhen Guo
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Computers, Campus > Binghamton University
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Enhanced Max Margin Learning on Multimodal Data Mining in a Multimedia Database
An Enhanced Max Margin Learning (EMML) framework that is much more efficient in learning with a much faster convergence rate, verified in empirical evaluations
Background:
The problem of multimodal data mining in a multimedia database can be addressed as a structured prediction problem where we learn the mapping from an input to the structured...
Published: 4/18/2024
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Inventor(s): Zhen Guo, Zhongfei Zhang
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Computers, Campus > Binghamton University
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