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A Closed-Loop Stimulation Controller for Exploring Neural States

A brand-new type of reinforcement learning algorithm RSS.HDBackground> Background: < Current day algorithms governing how medical devices deliver stimulation to patients have not changed in well over 50 years and cannot account for neurological variabilities across individuals that come about from differences in genetics, lifestyle factors,...
Published: 2/4/2025   |   Inventor(s): Ian Jordan, Il Park, Josue Nassar
Keywords(s):  
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Therapeutics, Technology Classifications > Medical Devices, Campus, Campus > Stony Brook University

Metal-mediated, Autolytic Amide Bond Cleavage for the Selective, Metal-Complexation Catalyzed, Controlled Release of Metallodrugs

Autolytic, metal complex-mediated amide bond cleavage for prodrug activation and synthesis of metallodrugs RSS.HDBackground> Background: < Clinically viable prodrugs release activated drug molecules at the site of interest, requiring close spatiotemporal control. Bond cleavage strategies for the release of the activated drug often incorporate...
Published: 2/4/2025   |   Inventor(s): Eszter Boros, Dariusz Śmiłowicz
Keywords(s):  
Category(s): Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Drug Delivery, Campus, Campus > Stony Brook University

System and Methods for Detecting, Capturing, and Measuring Nanoparticles

­Speeds the semiconductor manufacturing process by detecting particles smaller than 20nm before they have adhered to the silicon wafer. Background: The conventional method for of detecting particles during the semiconductor manufacturing process occurs only after the particles have adhered to silicon wafer. While that approach is easier because...
Published: 1/27/2025   |   Inventor(s): Gregory Denbeaux, Yashdeep Khopkar
Keywords(s): defect-tolerant semiconductor, Technologies
Category(s): Technology Classifications > Nanotechnology, Campus, Campus > SUNY Polytechnic Institute

Retrn Bioworks

­https://www.retrnbio.com/ https://www.retrnbio.com/ https://suny.technologypublisher.com/files/sites/retrn_bio_logo_primary_with_tag_full_color_dark.png https://suny.technologypublisher.com/files/sites/retrn_bio_logo_primary_with_tag_full_color_dark.png
Published: 4/4/2024   |   Inventor(s):  
Keywords(s): Startups
Category(s): Technology Classifications > Environment, Campus, Campus > SUNY Environmental Science & Forestry

Positron Emission Tomography (PET) Radiotracer

Composition, method and diagnostic use of positron imaging tomography imaging agent for bacterial infection detectionRSS.HDBackground> Background: <Positron emission tomography (PET) radiotracer is a diagnostic tool to detect bacterial infection in humans. A deficiency exists in clinical diagnostic tools capable of identifying bacterial infections...
Published: 2/1/2024   |   Inventor(s): Peter Tonge, Yong Li, Fereidoon Daryaee, Peter Smith-Jones, Labros Meimetis
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Campus, Campus > Stony Brook University

Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use

" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are diagnosed...
Published: 1/22/2024   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): Technologies
Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Campus, Campus > University at Albany

Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer

Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 9/26/2024   |   Inventor(s): Li Niu, Zhen Huang, Yan Han, Congzhou Wang, Jae Seon Park
Keywords(s): RNA, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus, Campus > University at Albany

Antiviral Compounds with a Unique Mechanism of Action

Host-directed viral inhibitors that target a highly conserved cellular machinery necessary for the viral life cycle. Background: HIV is a major global public health problem that lacks a cure, however available anti retrovirals have been successful in improving and extending the quality of life in patients. This success has recently encountered a set-back...
Published: 2/28/2024   |   Inventor(s): Carol Carter, Lorna Ehrlich
Keywords(s): Technologies
Category(s): Campus, Campus > Stony Brook University, Technology Classifications > Drug Design and/or Synthesis, Technology Classifications > Therapeutics

Additive Laser Metal Deposition on Carbon Materials

A novel substrate with high thermal conductivity improves powder-bed fusion metal additive manufacturing. Technology Overview: In current implementations of powder-bed fusion metal additive manufacturing, metal powders are directly fused to the metal substrate. To aid in the removal of the part, miniaturized truss-shaped support structures...
Published: 10/13/2021   |   Inventor(s): Scott Schiffres, Arad Azizi
Keywords(s): #SUNYresearch, CleanTech, Technologies, XCEED
Category(s): Technology Classifications > Clean Energy, Campus > Binghamton University, Campus

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