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Detection of Biomolecule Carbonylation

Rapid, accurate, and biocompatible oxidative damage detection probe Background: Oxidative stress is a characteristic of many disease states. One result of oxidative stress is an irreversible reaction of radicals with biomolecules that results in covalent addition of carbonyls to the biomolecules. The presence, location and amount of carbonylation...
Published: 12/28/2023   |   Inventor(s): Susan Tuttle, Kamalika Mukherjee
Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Materials and Chemicals

Labeling Microtubes in Live Cells

A technique that allows live visualization of microtubules without genetic manipulation or perturbing protein function Background: Microtubules are a fundamental component of the cytoskeleton of eukaryotic cells, and the observation of microtubule dynamics in live cells using fluorescence microscopy is of critical importance in studying cytoskeleton...
Published: 12/29/2023   |   Inventor(s): Susan Bane Tuttle, Kamalika Mukherjee
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Imaging, Campus > Binghamton University

A New Bioorthogonal Reaction

A fast, stable, versatile biomolecule coupling technology based on a bioorthogonal reaction that can occur at neutral pH and room temperature Background: “Click Chemistry” reactions are high yielding, wide in scope, create only byproducts that can be removed without chromatography, simple to perform, and can be conducted in easily removable...
Published: 7/13/2022   |   Inventor(s): Susan Bane Tuttle, Özlem Dilek, Kamalika Mukherjee
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Antibodies, Campus > Binghamton University

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