Novel Antifungal Agents with Dual Mechanism of Action
With a clear and growing unmet need, a novel mechanism of action, and demonstrated in vitro superiority over current standard-of-care agents, these novel boron-based antifungal agents represent a compelling early-stage opportunity with significant commercial and public health relevance.
Background:
Invasive fungal infections caused by opportunistic...
Published: 7/24/2026
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Inventor(s): Bhaskar Das, Joshua Nosanchuk, Daniel Miranda
Keywords(s): Chemistry, Featured, Healthcare, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Novel Small Molecule Agents for Glioblastoma
Brain-penetrant small molecule agents possessing a dual targeting mechanism of action (LonP1 and CT-L proteasome inhibition) that may overcome resistance mechanisms that currently plague standard of care treatments for brain tumors such as glioblastoma.
Background:
Malignant astrocytomas, including glioblastoma (GBM), represent highly aggressive intracranial...
Published: 7/10/2026
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Inventor(s): Bhaskar Das, Daniela Bota
Keywords(s): Chemistry, Nanotechnology, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Lipid nanoparticles for lung-targeted mRNA delivery
This technology is a new lipid nanoparticle system that can safely, specifically, and efficiently deliver mRNA to a patient’s lungs.
Background:
Therapeutics that deliver mRNA to a patient’s lungs offer significant potential for treating a broad spectrum of lung diseases. However, specifically and efficiently delivering mRNA to lung tissue...
Published: 6/22/2026
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Inventor(s): Yamin Li, David Popoola, Zhi Cao, Yuqin Men
Keywords(s): biomaterials, chemistry, drug delivery, gene therapy, nanoparticle drug delivery, RNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines
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Cyclopropane-Rich Ionic Liquid Compositions for High-Performance Fuel Systems
This technology creates renewable, high-energy-density liquid fuels using specially engineered molecules with multiple cyclopropane rings and energetic anions, offering safe, stable, and clean-burning alternatives to petroleum fuels for aviation and transport.
Background:
The field of high-energy-density fuels is critical for sectors such as aviation,...
Published: 6/12/2026
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Inventor(s): Arsalan Mirjafari
Keywords(s): aerospace, chemistry, fatty acids, Rocketry, Sustainability, Technologies
Category(s): Campus > SUNY Oswego, Technology Classifications > Clean Energy
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Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations.
Background:
Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 6/19/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
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Ambient-Temperature Direct Air Capture of Carbon Dioxide
Novel amine-based sorbents for carbon dioxide capture with enhanced oxidative and thermal stability
BACKGROUND:
Anthropogenic climate change presents an urgent threat to ecosystems, public health and economic stability. Even single degree increases in global temperatures can trigger irreversible impacts, ranging from biodiversity loss and food insecurity...
Published: 6/19/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Environment, Featured, Materials & Chemicals, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Self-Sustained Hydrogen Production
A self-sustained compact reactor for continuous hydrogen gas production from ammonia decomposition.
Background:
Hydrogen offers advantages as a clean and safe fuel for broad applications, but its storage and transport are expensive. Conversely, ammonia is an effective hydrogen carrier, as it contains 17.6% hydrogen by weight and can be economically...
Published: 6/19/2026
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Inventor(s): Amr Ibrahim, Miao Yu, Sung Hwan Park, Saman Emami Gerami
Keywords(s): Chemistry, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications, Technology Classifications > Energy, Technology Classifications > Engineering, Technology Classifications > Instrumentation, Technology Classifications > Materials and Chemicals
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Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)
Offers the potential of real-time small-sample analysis for a very large variety of applications.
Background:
Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....
Published: 1/30/2026
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Inventor(s): Rabi Musah
Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Environment, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents
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Lithium-7-Powered Nuclear Fission Subcritical Reactor: Safe Nuclear Power
A lithium-based fission reactor that generates safe, clean electricity while reducing the amount of discarded lithium batteries that end up in landfills.
Background:
Renewable energy sources such as solar, wind, and geothermal, have still failed to replace coal, oil, natural gas, and other fossil fuels, despite decades of technology development...
Published: 1/29/2026
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Inventor(s): Matthew Szydagis
Keywords(s): #SUNYresearch, aerospace, applied physics, atomic power, automotive, chemistry, clean energy, climate change, dark matter WIMPs, energy, engineering, environment, experimental physics, green energy, heating, ion beam physics, lithium ion battery, materials science and engineering, nuclear physics, physics, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Energy, Technology Classifications > Environment, Technology Classifications > Clean Energy, Technology Classifications > Engineering
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Identifying Wood Species from Chemical Signature
Quickly identifies wood species, both in the form of a log or as a product made from wood.
Background:
Currently, there are very strict national and international laws governing the buying and selling of wood and wood-based products. These laws are designed to curtail illegal trade in endangered tree species. However, it can be exceedingly difficult...
Published: 1/30/2026
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Inventor(s): Rabi Musah
Keywords(s): chemistry, forensics, statistical analysis, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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