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Temporal Control of CRISPR-Cas9 using Bio-orthogonal Chemistry.

This technology enables precise, time-controlled activation or deactivation of CRISPR-Cas9 genome editing using biocompatible chemical reactions, reducing off-target effects and improving the safety and accuracy of gene editing for research and therapeutic applications. Background: Genome editing technologies, particularly CRISPR-Cas9, have revolutionized...
Published: 5/5/2026   |   Inventor(s): Maksim Royzen, Bhoomika Pandit
Keywords(s): biochemistry, CRISPR, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Gene Therapy

Virus-Like Particles for mRNA Delivery

Virus-like particles have been engineered for drug delivery, gene editing applications, mRNA delivery and overcoming barriers in mouse lungs. Background: Recent biomedical research has shown increased interest in the use of virus-like particles as a drug delivery vehicle. Current viral vectors have been shown to cause adverse immunological responses,...
Published: 4/16/2026   |   Inventor(s): Sriram Neelamegham, Qi Yang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Gene Therapy, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

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