Fluorescent Peptides for Membrane Tension Reporting and Biomarkers
A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension.
Background:
The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...
Published: 4/16/2026
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Inventor(s): Thomas Suchyna, Sergei Sukharev
Keywords(s): Featured, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials
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Simulation-Based Wildfire Spread Modeling Tool for Community-Scale Risk Assessment (SWUIFT)
This technology enables community-scale wildfire risk assessment using a simulation-based model that predicts fire spread and damage within the wildland-urban interface, supporting proactive mitigation and emergency planning.
BACKGROUND:
Communities and infrastructure owners currently lack effective tools to estimate wildfire spread and resulting...
Published: 4/16/2026
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Inventor(s): Negar Elhami-Khorasani, Fernando Szasdi-Bardales, Nima Masoudvaziri
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Agriculture, Technology Classifications > Environment
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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)
This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription.
BACKGROUND:
Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 4/16/2026
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Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics
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Determining the Percentage of Recycled Plastic Content in a Plastic Product
A device to determine the percentage of recycled plastic content in a manufactured plastic product.
BACKGROUND:
As global plastic waste continues to rise, accurately identifying and quantifying recycled content in plastic products is critical for developing a circular economy. At present, there is no method that can accurately determine the percentage...
Published: 4/16/2026
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Inventor(s): Amit Goyal, Thomas Thundat, Yaoli Zhao, Charuvahan Adhivarahan, Karthik Dantu, Chandra Lekha Jyothula
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Sensors
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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties
BACKGROUND:
The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Apelin-Receptor (APJ) Antagonists
A series of stable, small molecule compounds that inhibit an alternative (non-VEGF) angiogenic pathway that is overexpressed in a variety of cancers.
Background:
Antiangiogenic drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway are widely used to treat solid tumors and ocular conditions such as wet AMD. However, anti-VEGF...
Published: 4/16/2026
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Inventor(s): Youngjae You, Sukyung Woo, Ganesh Bist, Ahmed Elsheikh
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Design and Synthesis
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Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers
BACKGROUND:
There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials.
TECHNOLOGY...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
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Novel Fusion Protein Vaccine for Moraxella Catarrhalis Infections
A fusion protein vaccine designed to prevent COPD exacerbations and pediatric acute otitis media.
Background:
Respiratory infections caused by Moraxella catarrhalis (Mcat) represent a growing public health concern. In children, Mcat is a leading cause of otitis media, a common middle ear infection affecting most children by age three, frequently...
Published: 4/16/2026
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Inventor(s): Timothy Murphy, Patricia Weber
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Antibodies
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Beamforming Device and Architectures for Large Language Model Enabled Personal Monitoring
WisperWatcher is a wearable audio-based system that automatically monitors eating behavior by capturing and analyzing mastication and swallowing sounds. Leveraging beamforming techniques combined with Large Audio-Language Models (LALM), it provides accurate, real-time insights into food intake, meal timing, and user disposition while minimizing user...
Published: 4/16/2026
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Inventor(s): Alexander Gherardi, Wenyao Xu, Wei Bo, Shuwei Hou
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Medical Devices
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Optimizing Deep Neural Networks for EEG-Based Speech Recognition: A Multimodal Approach to Assistive Communication
A deep learning-based multimodal framework that combines EEG and audio signals to decode spoken phrases. By integrating neural activity with speech audio, the system improves recognition for individuals with neurological impairments, such as Parkinson's disease, ALS, or cerebral palsy, and enhances robustness in noisy environments. The framework...
Published: 4/16/2026
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Inventor(s): Anarghya Das, Puru Soni, Wenyao Xu
Keywords(s): Assistive Technology, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Medical Devices
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