Glycosyltransferase Mutation-Activity Landscape
A streamlined high-throughput platform for engineering glycosyltransferases and glucosidases
Background:
Glycosyltransferases are enzymes that commonly transfer monosaccharides to proteins and lipid scaffolds. These enzymes constitute ~2% of the coding human genome, representing over 200 proteins. Mutations in glycosyltransferases lead to disease;...
Published: 9/2/2025
|
Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Biotechnology, Diagnostic, Pharmaceutical, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biomedical Science and Engineering
|
Reduction of Lipid Accumulation Reverses Aging
Therapeutic strategy to treat age-related cardiovascular disease and restore cardiovascular function through maintenance of lipid homeostasis.
Background:
Age is a key risk factor for cardiovascular disease such as atherosclerosis, which is characterized by endothelial dysfunction, extracellular matrix remodeling, lipid accumulation, chronic inflammation...
Published: 8/28/2025
|
Inventor(s): Stelios Andreadis, Yulun Wu, Pihu Mehrotra
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
|
Method for Forming a Ceramic Aerogel
This technology is a scalable roll-to-roll (R2R) additive manufacturing of silica-carbon composite aerogel for building insulation materials that could exceed existing silica aerogel’s R-value at near standard temperature and pressure conditions and ~90% reduction of the unit price . The new composite is made of silica aerogel and carbon. The...
Published: 8/20/2025
|
Inventor(s): Shenqiang Ren, Ruizhe Yang, Bingbo Chai
Keywords(s):
Category(s): Campus > University at Buffalo, Technology Classifications > Energy Conservation, Technology Classifications > Materials and Chemicals
|
Smart Metal-Graphene Hybrid Reflectarray at THz Frequencies
Four technologies work in unison (source, modulator, antenna, reflector) to increase the propagation of upper band 5G (i.e., 100 to 300 GHz).
Background:
In order to continue the exponential rise in wireless data rates, terabit-per-second links are expected to become a reality within the next five years. The exploration of higher frequency bands,...
Published: 8/15/2025
|
Inventor(s): Erik Einarsson, Josep Jornet, Arjun Singh, Ngwe Thawdar, Michael Andrello
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Electronics, Technology Classifications > Wireless Technologies
|
A Flexible Multiplexed Amplifier for Multichannel Wearable Biopotential Devices
A compact, multiplexed amplifier architecture for wearable biopotential devices, enabling efficient, multi-channel data processing in a miniaturized, flexible format.
Background:
High-density biopotential measurement devices, such as EMGs and EEGs, typically require large and cumbersome amplifiers, limiting their applicability in wearable technologies....
Published: 8/20/2025
|
Inventor(s): Filip Stefanovic
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Medical Devices, Technology Classifications > Electronics
|
Device and Methods for Telehealth Wound Care
An inexpensive, hand-held optical device capable of imaging wounds for telehealth monitoring of healing and vascular structure.
Background:
Open sores and wound healing are a pressing concern in medical care of limited mobility patients. For instance, diabetic foot ulcers are associated with a 25% five year mortality rate as well as other complications....
Published: 7/22/2025
|
Inventor(s): Wenyao Xu, Jun Xia, Alexander Gherardi, Tianyu Chen
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging
|
High-Frequency, Device-Free mmWave Facial Landmark Sensing
A high-resolution, non-contact facial landmark tracking system that uses millimeter wave (mmWave) technology to achieve precise and efficient facial sensing.
Background:
MicroFace introduces a novel mmWave-based system for high-resolution, non-contact facial landmark tracking. This system addresses the existing challenge of precise and efficient...
Published: 7/22/2025
|
Inventor(s): Wenyao Xu, Chenhan Xu
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Sensors, Technology Classifications > Information Technology
|
Self-Sustained Hydrogen Production
A self-sustained compact reactor for continuous hydrogen gas production from ammonia decomposition.
Background:
Hydrogen offers advantages as a clean and safe fuel for broad applications, but its storage and transport are expensive. Conversely, ammonia is an effective hydrogen carrier, as it contains 17.6% hydrogen by weight and can be economically...
Published: 7/22/2025
|
Inventor(s): Amr Ibrahim, Miao Yu, Sung Hwan Park, Saman Emami Gerami
Keywords(s): Chemistry, Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications, Technology Classifications > Energy, Technology Classifications > Engineering, Technology Classifications > Instrumentation, Technology Classifications > Materials and Chemicals
|
Antimicrobial Compositions and Combination Therapies
Compositions and methods to combat drug-resistant Pseudomonas aeruginosa infections.
Background:
Antibiotic resistance is an urgent and growing health threat. Pseudomonas aeruginosa is known to cause a variety of infections in both immunocompetent and immunocompromised individuals, but especially the latter. It utilizes both intrinsic and acquired...
Published: 7/22/2025
|
Inventor(s): Mark Sutton, Brian Tsuji, Anthony Berdis
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines
|
Easily Produced Nanoscale Hot Spots for More Sensitive Raman Scattering Using Liquid Metal Structures
A novel nanophotonic sensor that enhances Raman scattering signals by several orders of magnitude by creating nanoscale hot spots formed by liquid metal.
Background:
Analytes in the hot spots of such nanophotonic sensors will experience drastically enhanced interactions with the incident light, and therefore produce much more optical sensing signals....
Published: 7/22/2025
|
Inventor(s): Peter Liu, Xianglong Miao, Shreyan Datta
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering
|