Tools to Predict Clinical Immunogenicity
In vitro tools for predicting clinical immunogenicity of subcutaneously administered antigens, whether for therapeutic or prophylactic applications.
Background:
Immunogenicity, the propensity of a product to elicit an immune response to itself or related structures, may be desirable (e.g. vaccine candidates) or undesirable...
Published: 7/9/2026
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Inventor(s): Sathy Balu-Iyer, Aditi Venkatesh
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Novel Small Molecule Anabolic Agents for Osteoporosis
-Analogs of a naturally occurring phytoestrogen that hold promise for the treatment of osteoporosis and other conditions impacting peri- and post-menopausal women.
Background:
Menopause significantly speeds bone loss and increases the risk of osteoporosis, a condition characterized by decreased bone mineral density and which impacts more than 200M...
Published: 7/9/2026
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Inventor(s): Bhaskar Das, Hiranmoy Das
Keywords(s): Pharmaceutical, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Novel Small Molecule Agents for Glioblastoma
Brain-penetrant small molecule agents possessing a dual targeting mechanism of action (LonP1 and CT-L proteasome inhibition) that may overcome resistance mechanisms that currently plague standard of care treatments for brain tumors such as glioblastoma.
Background:
Malignant astrocytomas, including glioblastoma (GBM), represent highly aggressive intracranial...
Published: 7/10/2026
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Inventor(s): Bhaskar Das, Daniela Bota
Keywords(s): Chemistry, Nanotechnology, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
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Methods for Low-Overhead, Fault-Tolerant CNOT Operations.
Methods for Low-Overhead, Fault-Tolerant CNOT Operations between two Non-Nearest Neighboring Logical Qubits
Background:
The term Noisy Intermediate-Scale Quantum (NISQ) has been used to describe the current state of quantum computing technology because (1) qubits are highly error prone; and (2) the number of qubits in a single (monolithic) Quantum...
Published: 6/29/2026
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Inventor(s): Chunming Qiao, Sean Grzenda
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Computers, Technology Classifications > Quantum Computing
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Flexible Nanophotonic Cavity-Enhanced Infrared Photodetectors Employing Double Quantum Wells
Double-quantum-well infrared photodetectors (DQWIPs) integrated with nanophotonic cavities enable highly responsive mid-infrared detection through enhanced intersubband absorption in the thin semiconductor heterostructure. Additionally, the technology is compatible with flexible substrates.
Background:
Quantum Well Infrared Photodetectors (QWIPs)...
Published: 6/25/2026
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Inventor(s): Peter Liu, Puspita Paul
Keywords(s): Imaging: Medical Imaging, Instrumentation, Night vision and thermal imaging, Optics, Research Tool, Sensors, Surveillance, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Electronics, Technology Classifications > Engineering, Technology Classifications > Semiconductor Devices and Manufacturing, Technology Classifications > Quantum Computing
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Reduction of Lipid Accumulation Reverses Aging
Therapeutic strategy to treat age-related cardiovascular disease and restore cardiovascular function through maintenance of lipid homeostasis.
Background:
Age is a key risk factor for cardiovascular disease such as atherosclerosis, which is characterized by endothelial dysfunction, extracellular matrix remodeling, lipid accumulation, chronic inflammation...
Published: 6/19/2026
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Inventor(s): Stylianos Andreadis, Yulun Wu, Pihu Mehrotra
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
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ALD-enabled High-Performance Membranes for Gas Separation
Polymer-based membranes developed with high H2/CO2 selectivity using facile surface nanoengineering for higher energy efficiency and lower cost production.
Background:
Isolation of CO2 from mixtures containing H2 is a critical gas separation, producing 94 million metric tons of H2 worldwide and valued at $170 billion in 2021. This market will continue...
Published: 6/19/2026
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Inventor(s): Haiqing Lin, Won-IL Lee, Chang-Yong Nam, Leiqing Hu, Kim Kisslinger, Vinh Bui, Ashwanth Subramanian
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Clean Energy, Technology Classifications > Environment
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Novel Test for Non-HLA-based-rejection in Organ Transplantation
Luminex-based immunoassay for prediction of non-HLA determinants of kidney transplant graft rejection
Background:
End-stage kidney disease, also known as end-stage renal disease or kidney failure, affects over 800,000 people in the US. It is rapidly fatal without treatment, but can be treated palliatively with dialysis or curatively by kidney transplant....
Published: 6/19/2026
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Inventor(s): Lakshmanan Suresh, John Tomaszewski
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays
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Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations.
Background:
Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 6/19/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
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Production of Salivary Gland Epithelial Progenitors and Acinar Organoids
Human iPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function.
Background:
Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 6/19/2026
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Inventor(s): Stylianos Andreadis, Ronel Zachariah Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays
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