Novel test for Non-HLA-based-rejection in organ transplantation
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Luminex-based immunoassay for prediction of non-HLA determinants of kidney transplant graft rejection
Background:
End-stage kidney disease, also known as end-stage renal disease or kidney failure, affects over 800,000 people in the US. It is rapidly fatal without treatment, but can be treated palliatively with dialysis or...
Published: 6/2/2026
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Inventor(s): Lakshmanan Suresh, John Tomaszewski
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays
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Nanoporous Materials for Direct Air Capture
An amine-based ultrathin polyamide coating for direct carbon dioxide capture from air and point sources with low carbon dioxide concentrations.
Background:
Direct air capture (DAC) technologies allow extraction of carbon dioxide from the atmosphere and storage or conversion to value-added chemicals through catalysis. DAC materials must demonstrate...
Published: 5/13/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Environment
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Production of Salivary Gland Epithelial Progenitors and Acinar Organoids
Human iPSC-based tissue engineering system to develop salivary gland epithelial progenitors used to construct acinar organoids that mimic glandular microarchitecture and function.
Background:
Organoids are three-dimensional cell constructs that replicate the complicated tissue microarchitecture of specialized epithelial tissues. These constructs...
Published: 5/13/2026
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Inventor(s): Stelios Andreadis, Ronel Samuel, Olga Baker, Kihoon Nam
Keywords(s): Biomedical Engineering, Biotechnology, Medical Devices, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Screens and Assays
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Fluorescent Peptides for Membrane Tension Reporting and Biomarkers
A peptide-based probe technology that enables real-time, non-invasive fluorescent detection and quantitation of cell membrane tension.
Background:
The 2021 Nobel Prize in Physiology or Medicine was awarded for the discovery of Piezo channels, mechanosensitive ion channels that respond to cell membrane tension, translating mechanical force directly...
Published: 5/15/2026
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Inventor(s): Thomas Suchyna, Sergei Sukharev
Keywords(s): Featured, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Biological Materials
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Simulation-Based Wildfire Spread Modeling Tool for Community-Scale Risk Assessment (SWUIFT)
This technology enables community-scale wildfire risk assessment using a simulation-based model that predicts fire spread and damage wihtin the wildland-urban interface, supporting proactive mitigation and emergency planning.
BACKGROUND:
Communities and infrastructure owners currently lack effective tools to estimate wildfire spread and resulting...
Published: 4/24/2026
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Inventor(s): Negar Elhami-Khorasani, Fernando Szasdi-Bardales, Nima Masoudvaziri
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Agriculture, Technology Classifications > Environment
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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)
This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription.
BACKGROUND:
Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 4/16/2026
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Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics
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Determining the Percentage of Recycled Plastic Content in a Plastic Product
A device to determine the percentage of recycled plastic content in a manufactured plastic product.
BACKGROUND:
As global plastic waste continues to rise, accurately identifying and quantifying recycled content in plastic products is critical for developing a circular economy. At present, there is no method that can accurately determine the percentage...
Published: 4/30/2026
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Inventor(s): Amit Goyal, Thomas Thundat, Yaoli Zhao, Charuvahan Adhivarahan, Karthik Dantu, Chandra Lekha Jyothula
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Sensors
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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties
BACKGROUND:
The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Apelin-Receptor (APJ) Antagonists
A series of stable, small molecule compounds that inhibit an alternative (non-VEGF) angiogenic pathway that is overexpressed in a variety of cancers.
Background:
Antiangiogenic drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway are widely used to treat solid tumors and ocular conditions such as wet AMD. However, anti-VEGF...
Published: 4/16/2026
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Inventor(s): Youngjae You, Sukyung Woo, Ganesh Bist, Ahmed Elsheikh
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Design and Synthesis
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Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers
BACKGROUND:
There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials.
TECHNOLOGY...
Published: 4/16/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
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