Sparse Poisson Regression Approach for Unmixing Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more.
Background:
Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 2/12/2024
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Inventor(s): Alex Valm, Yunlong Feng
Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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Identification of Body Fluids Using Raman Spectroscopy
A one-step confirmatory test to identify forensic body fluid samples.
Technology Overview:
This simple, non-destructive method for positive identification of all forensic body fluid types, is based on Raman Spectroscopy,a light scattering phenomenon that provides a unique molecular vibrational signature of a material. The patented technology...
Published: 3/12/2024
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Inventor(s): Igor Lednev, Kelly Virkler
Keywords(s): 3D printing, blood, evidentiary sample, fluorescence spectroscopy, forensics, oral epithelial cells, Raman microscopy, Raman spectroscopy, saliva, semen, sperm, sweat, TAF, vaginal epithelial cells, vaginal fluid
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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