Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research.
Background:
Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/26/2026
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Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
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A 3D printable mini-gel electrophoresis system and methods for use
This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources.
Background:
Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 3/26/2026
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Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya
Keywords(s): 3D printing, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
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Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications.
Background:
Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/26/2026
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Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): aptamers, DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
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Methods for detecting RNA modifications with DNA nanoswitches
This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications.
Background:
RNA modifications, such as methylation, play critical roles in gene regulation, cellular...
Published: 3/26/2026
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Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden
Keywords(s): DNA nanoswitches, RNA modifications, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis
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Peptide Therapeutic Against HIV
This technology presents a computationally evolved peptide therapeutic that targets human lysine tRNA to disrupt the HIV-1 replication cycle.
Background:
HIV-1 replication poses a significant challenge for therapeutic intervention due to the virus’s complex interaction with host cellular mechanisms. Existing treatments often face limitations...
Published: 3/27/2026
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Inventor(s): Paul Agris, Carol Hall, Xingqing Xiao
Keywords(s): HIV/AIDS, therapeutic targets
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Albany
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Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects.
Background:
The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 3/5/2026
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Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
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Integrating AI in Back Injury Prevention
This wearable technology integrates sensors into a back brace and shoe inserts to monitor posture and movement. Using AI-driven analysis, it provides real-time feedback via a software application, helping Direct Care Workers prevent the risk of back injuries during lifting and transfer tasks.
Background:
Workplace injuries, particularly musculoskeletal...
Published: 2/25/2026
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Inventor(s): Yuchi Young
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Artificial Intelligence, Technology Classifications > Healthcare
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LOW GLOBAL WARMING COMBINED HVAC AND HOT WATER SYSTEM FOR RESIDENTIAL APPLICATIONS
This technology uses transcritical CO2 as a working fluid to efficiently provide both heating, cooling, and hot water in a single combined HVAC and water heating system.
Background:
Heating, ventilation, and air conditioning (HVAC) systems, along with water heating units, are essential components in residential and commercial buildings, providing...
Published: 2/18/2026
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Inventor(s): Jorge Gonzalez-Cruz, Prathap Ramamurthy, David Garraway
Keywords(s): automated systems, control systems, heating, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Clean Energy, Technology Classifications > Energy Conservation
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Deuterized Low-K Dielectric Materials for TDDB Mitigation
Simple, scalable and inexpensive process to replace the hydrogen in low-k dielectrics with deuterium to improve semiconductor performance. Background: Low-k dielectrics are a class of materials used in the manufacture of nanoscale semiconductor devices. The problem with low-k dielectrics is that they are susceptible to a phenomenon known as time dependent...
Published: 3/24/2026
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Inventor(s): James Lloyd, Patrick Lenahan, Niaz Mahmud
Keywords(s): nanotechnology, semiconductors
Category(s): Technology Classifications > Nanotechnology, Campus > University at Albany
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Designable Polymer Substrates for Correlative Light and Electron Microscopy
This technology uses customizable, transparent polymer substrates with precise pores and indexing patterns to facilitate correlative light and electron microscopy, enabling accurate correlation of live cell fluorescence imaging with ultrastructural details of sectioned cells on permeable supports for advanced biological research.
Background:
Correlative...
Published: 3/26/2026
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Inventor(s): Haixin Sui, Yubing Xie, Dipayan Sarkar, Adam Koplas, Julia Garrison, Natalya Tokranova, Yanfeng Zhang
Keywords(s): correlative light and electron microscopy (CLEM), Polymer blends Analysis, Technologies, visible light polymerization
Category(s): Campus > University at Albany, Technology Classifications > Imaging, Technology Classifications > Medical Imaging
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