Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects.
Background:
The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 1/15/2026
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Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
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The Neutron Activation Reactor, Lithium (NARLi)
The Neutron Activation Reactor, Lithium (NARLi), generates clean electricity by using low-energy neutrons to activate lithium-7, producing heat without nuclear fission or long-lived radioactive waste, and can use recycled lithium from batteries as fuel.
Background:
Nuclear energy has long been recognized as a powerful means of generating large-scale...
Published: 12/29/2025
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Inventor(s): Matthew Szydagis, Eric Bentsen
Keywords(s): energy, Technologies
Category(s): Campus, Campus > University at Albany, Technology Classifications > Clean Energy
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Therapeutic backbone and scaffold modification in the physiological environment
This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications.
Background:
Proteins and polypeptides play a central role...
Published: 12/19/2025
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Inventor(s): Qiang Zhang
Keywords(s): antibody therapy, GLP-1 secretion, Insulin, protein engineering, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
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Method and Apparatus for Simultaneous Acquisition of Electrocardiogram Signals and Electrical Impedance Tomography Data
A new imaging technology that can be used with an electrocardiogram to aid the diagnosis and treatment of cardiac and pulmonary conditions.
Background:
Electrical impedance tomography (EIT) is a new imaging technology that can be used with an electrocardiogram (EKG) to aid the diagnosis and treatment of cardiac and pulmonary conditions. Examples...
Published: 10/29/2025
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Inventor(s): Gary Saulnier, Ahmed Abdelwahab, Omid Rajabi Shishvan, Nilton Barbosa da Rosa
Keywords(s): electrical impedance tomography, electrocardiogram, heart/lung function, medical equipment, medical imaging, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging
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Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics
This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications.
Background:
There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...
Published: 10/24/2025
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Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Bioinformatics, Technology Classifications > Artificial Intelligence, Technology Classifications > Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Dental
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RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes.
Background:
Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 11/6/2025
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Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses
This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases.
Background:
In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 10/29/2025
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Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Raman Spectroscopy for Testing Stability of RNA-based Vaccines and Drugs
A fast, less expensive, and more reliable method for assessing mRNA degradation in vaccines, that can also be used as a tool for the development of new RNA-based therapeutics.
Background:
The development of mRNA-based vaccines for COVID-19 offers the potential for a new medical paradigm based on RNA technology. Unfortunately, these drugs require...
Published: 10/29/2025
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Inventor(s): Igor Lednev, Alexander Shekhtman, Lamyaa Almehmadi, Sergei Reverdatto
Keywords(s): drug stability, mRNA, mRNA stability, Raman spectroscopy, RNA, Technologies, vaccine stability, vaccines
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
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Use of Quercetin and Related Flavonoids for the Treatment of Myotonic Dystrophy Types 1 and 2
A novel flavonoids-based therapeutic strategy for the treatment of myotonic dystrophy and potentially repeat expansion disorders. Background:
Myotonic dystrophy (DM) is the most common form of adult muscular dystrophy. It is a multisystemic disorder affecting nearly all organs including muscles, brain, heart, eyes, and the GI tract, among others....
Published: 10/24/2025
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Inventor(s): John Berglund, Subodh Mishra, Kaalak Reddy, John Cleary
Keywords(s): drug discovery, drug efficacy, myotonic dystrophy, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
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Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses.
Background:
Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Lifeng Zhou
Keywords(s): DNA, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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