Liquid Biopsy Detection of TF-Ag-α-Positive Cancer-Associated Exosomes
A liquid biopsy assay detecting TF-Ag-α–positive tumor-derived exosomes for cancer screening, early detection and treatment monitoring.
Background:
Cancer diagnostics are rapidly evolving as early detection and treatment monitoring are critical to improving patient outcomes. Traditional methods such as imaging and tissue biopsies...
Published: 7/29/2026
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Inventor(s): Yun Wu, Grace Dy, Kate Rittenhouse-Olson
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Engineering, Technology Classifications > Medical Devices, Technology Classifications > Sensors
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Luminescent biosensor for detection of nucleotide sequences, small molecules, and proteins at the point-of-care
This technology is a modular, luminescent biosensor that rapidly detects DNA, RNA, small molecules, and proteins at the point of care, using a visible color change measurable by a smartphone, enabling fast, sensitive, and equipment-free diagnostics.
Background:
Molecular diagnostics is a rapidly evolving field that plays a critical role in the detection...
Published: 7/27/2026
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Inventor(s): Harsimranjit Sekhon, Stewart Loh
Keywords(s): bio/chemical sensors, bioluminescence, biomarker diagnostics, biosensor, nanoluciferase, Technologies, therapeutic drug monitoring, Virus Detection
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
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Novel EGFR Truncations as Biomarker and Target
Three mutations that could be used as biomarkers for patient's drug responses or for tumor therapeutic targets Background: Three new truncation mutants have been discovered in primary human tumors and cell lines. These mutants may possess oncogenic activities and render some tumors resistant to certain inhibitors. These newly discovered mutants...
Published: 7/21/2026
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Inventor(s): Edward Chan, James Keller
Keywords(s): EGFR471, EGFR660, EGFR768, Technologies, truncated EGFR
Category(s): Technology Classifications > Diagnostics, Campus > Stony Brook University
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Hand-held Glucometer based pathogen and other biomarker detection using RNA switches
This technology uses engineered RNA switches and CRISPR to detect various biomarkers, converting their presence into glucose that can be measured with a standard handheld glucometer, enabling rapid, low-cost, and versatile point-of-care diagnostics.
Background:
Molecular diagnostics is a rapidly evolving field that plays a crucial role in the detection...
Published: 7/9/2026
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Inventor(s): Mehmet Yigit, Emmett Hanson, Mahla Lashkari, Natalie Connell
Keywords(s): biomarkers, diagnostics, RNA-switch, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Procedure for Pre-Clinical Continuous EEG/ECG Monitoring
This technology introduces a novel surgical procedure, custom implant, and wiring harness for continuous electroencephalogram (EEG) and electrocardiogram (ECG) monitoring in conscious unrestrained animals. The animal is chronically implanted with subdermal electrodes and connected to a durable wiring system to capture high-quality physiological data....
Published: 6/29/2026
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Inventor(s): David Auerbach, Kyle Wagner, Laura Williams
Keywords(s): animal models, animal studies, bioengineering, biomedical science, biosensor, electrocardiogram, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures
This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures.
Background:
Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...
Published: 6/29/2026
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Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner
Keywords(s): biomarkers, epilepsy, seizures, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Video-Based Behavioral Analysis to Facilitate Early Autism Diagnosis
This technology uses a mobile app to record children’s behavior at home, then analyzes the videos with AI to help screen for autism early, providing quick, accessible feedback to families and supporting clinicians with objective behavioral data.
Background:
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized...
Published: 6/12/2026
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Inventor(s): Xin Li, Shuo Wang
Keywords(s): artificial intelligence, autism spectrum disorder, biomarker diagnostics, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Novel Test for Non-HLA-based-rejection in Organ Transplantation
Luminex-based immunoassay for prediction of non-HLA determinants of kidney transplant graft rejection
Background:
End-stage kidney disease, also known as end-stage renal disease or kidney failure, affects over 800,000 people in the US. It is rapidly fatal without treatment, but can be treated palliatively with dialysis or curatively by kidney transplant....
Published: 6/19/2026
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Inventor(s): Lakshmanan Suresh, John Tomaszewski
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays
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ATR_FTIR spectroscopy of saliva and machine learning as a screening test for the Sjögren disease
This technology uses saliva analysis with infrared spectroscopy and machine learning to provide a fast, non-invasive, and accurate test for Sjögren’s Disease, filtering out unreliable data to improve diagnosis and potentially screen for other diseases.
Background:
Sjögren’s disease is a chronic autoimmune disorder that primarily...
Published: 5/28/2026
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Inventor(s): Igor Lednev, Bhavikkumar Vyas, Jürgen Popp, Oleg Ryabchykov
Keywords(s): diagnostics, Salivary biomarkers, Sjogren Disease, spectroscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Spectroscopic Method for Diagnostics of Alzheimer's Disease
This technology provides a non-invasive, spectroscopic method using Raman spectroscopy to diagnose and monitor Alzheimer’s disease by analyzing biochemical changes in blood serum.
Background:
Alzheimer’s disease presents significant diagnostic challenges, often requiring invasive or costly procedures with limited early detection capabilities....
Published: 7/23/2026
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Inventor(s): Igor Lednev
Keywords(s): Alzheimer's, blood, diagnostics, neurodegeneration, Raman spectroscopy, statistical analysis, TAF, Technologies, vibrational spectroscopy
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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