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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)

This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription. BACKGROUND: Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 4/16/2026   |   Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics

Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers

Novel platform for biomaterials development with advanced physiological properties BACKGROUND: The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 4/16/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents

Functionalized Dendrimers with Regioselective Reactivity

Novel compositions of zwitterionic dendrimers and derived polymers BACKGROUND: There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials. TECHNOLOGY...
Published: 4/16/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics

Improving the sensitivity and range of detection with ligation of DNA nanoswitches

This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/26/2026   |   Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering

A 3D printable mini-gel electrophoresis system and methods for use

This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 3/26/2026   |   Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya
Keywords(s): 3D printing, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics

Expanding DNA nanoswitch utility with detection by aptamers

This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/26/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): aptamers, DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering

Methods for detecting RNA modifications with DNA nanoswitches

This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications. Background: RNA modifications, such as methylation, play critical roles in gene regulation, cellular...
Published: 3/26/2026   |   Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden
Keywords(s): DNA nanoswitches, RNA modifications, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis

Method for Sampling Terahertz Pulses in the Time-Domain Using Modulated Difference-Frequency in the Repetition Rates of Femtosecond Lasers

050-9317 Portable Handheld Spectral Reflection (PHASR) Scanner to Allow THz Time-Domain Spectroscopic (THz-TDS) Imaging of Burn Wounds A handheld terahertz (THz) spectroscopy and 3D imaging device designed for noninvasive evaluation of burn injury severity Background: Burn injuries pose a substantial public health challenge, leading to hundreds...
Published: 4/15/2026   |   Inventor(s): Mohammad Arbab, Zachery Harris
Keywords(s):  
Category(s): Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Optics and Photonics, Campus > Stony Brook University

A method for fast, sensitive, and quatitaive imaging of blood flow networks

050- 8968 A Method for Fast, Sensitive, and Quantitative Imaging of Blood Flow Networks An optical coherence Doppler tomography (OTD) system designed to image capillary flow with high speed and signal quality Background: The ability to quantitatively image three-dimensional blood flow, particularly within micro-circulatory networks like capillaries,...
Published: 4/15/2026   |   Inventor(s): Yingtian Pan, Congwu Du, Wei Chen
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Medical Imaging, Technology Classifications > Optics and Photonics, Campus, Campus > Stony Brook University

DEVICE FOR ORAL FLUID COLLECTION CONSISTING OF ABSORBANT MATERIAL AND NESTED TUBES REQUIRING CENTRIFUGATION

This is a simple, low-cost device using absorbent material and nested tubes to collect clean, mucous-free oral fluid samples by centrifugation, making sample collection easier, more hygienic, and affordable for labs and research. Background: Oral fluid collection is an essential process in various fields, including clinical diagnostics, biomedical...
Published: 2/13/2026   |   Inventor(s): Aaron Glass
Keywords(s): saliva, Salivary biomarkers, specimen collection, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices, Technology Classifications > Diagnostics
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