Hand-held Glucometer based pathogen and other biomarker detection using RNA switches
This technology uses engineered RNA switches and CRISPR to detect various biomarkers, converting their presence into glucose that can be measured with a standard handheld glucometer, enabling rapid, low-cost, and versatile point-of-care diagnostics.
Background:
Molecular diagnostics is a rapidly evolving field that plays a crucial role in the detection...
Published: 7/9/2026
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Inventor(s): Mehmet Yigit, Emmett Hanson, Mahla Lashkari, Natalie Connell
Keywords(s): biomarkers, diagnostics, RNA-switch, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Procedure for Pre-Clinical Continuous EEG/ECG Monitoring
This technology introduces a novel surgical procedure, custom implant, and wiring harness for continuous electroencephalogram (EEG) and electrocardiogram (ECG) monitoring in conscious unrestrained animals. The animal is chronically implanted with subdermal electrodes and connected to a durable wiring system to capture high-quality physiological data....
Published: 6/29/2026
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Inventor(s): David Auerbach, Kyle Wagner, Laura Williams
Keywords(s): animal models, animal studies, bioengineering, biomedical science, biosensor, electrocardiogram, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures
This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures.
Background:
Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...
Published: 6/29/2026
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Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner
Keywords(s): biomarkers, epilepsy, seizures, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
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Video-Based Behavioral Analysis to Facilitate Early Autism Diagnosis
This technology uses a mobile app to record children’s behavior at home, then analyzes the videos with AI to help screen for autism early, providing quick, accessible feedback to families and supporting clinicians with objective behavioral data.
Background:
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized...
Published: 6/12/2026
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Inventor(s): Xin Li, Shuo Wang
Keywords(s): artificial intelligence, autism spectrum disorder, biomarker diagnostics, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Novel Test for Non-HLA-based-rejection in Organ Transplantation
Luminex-based immunoassay for prediction of non-HLA determinants of kidney transplant graft rejection
Background:
End-stage kidney disease, also known as end-stage renal disease or kidney failure, affects over 800,000 people in the US. It is rapidly fatal without treatment, but can be treated palliatively with dialysis or curatively by kidney transplant....
Published: 6/19/2026
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Inventor(s): Lakshmanan Suresh, John Tomaszewski
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Diagnostics, Technology Classifications > Screens and Assays
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ATR_FTIR spectroscopy of saliva and machine learning as a screening test for the Sjögren disease
This technology uses saliva analysis with infrared spectroscopy and machine learning to provide a fast, non-invasive, and accurate test for Sjögren’s Disease, filtering out unreliable data to improve diagnosis and potentially screen for other diseases.
Background:
Sjögren’s disease is a chronic autoimmune disorder that primarily...
Published: 5/28/2026
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Inventor(s): Igor Lednev, Bhavikkumar Vyas, Jürgen Popp, Oleg Ryabchykov
Keywords(s): diagnostics, Salivary biomarkers, Sjogren Disease, spectroscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Spectroscopic Method for Diagnostics of Alzheimer's Disease
This technology provides a non-invasive, spectroscopic method using Raman spectroscopy to diagnose and monitor Alzheimer’s disease by analyzing biochemical changes in blood serum.
Background:
Alzheimer’s disease presents significant diagnostic challenges, often requiring invasive or costly procedures with limited early detection capabilities....
Published: 5/6/2026
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Inventor(s): Igor Lednev
Keywords(s): Alzheimer's, blood, diagnostics, neurodegeneration, Raman spectroscopy, statistical analysis, TAF, Technologies, vibrational spectroscopy
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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Diagnosing Alzheimer's via Raman Spectroscopic Analysis of Saliva
This technology provides a non-invasive method for early detection of cognitive diseases using spectroscopic analysis of saliva samples combined with advanced statistical and neural network models.
Background:
Cognitive diseases such as Alzheimer's and mild cognitive impairment (MCI) represent significant challenges in healthcare due to their...
Published: 5/5/2026
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Inventor(s): Igor Lednev, Nicole Ralbovsky, Cay Anderson-Hanley
Keywords(s): Alzheimer's, diagnostics, saliva, solar cells, TAF, Technologies
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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Language-Agnostic Voice Biomarker Platform for Early Detection of Alzheimer’s Disease and Related Dementias (GloVoAD)
This technology enables early, non-invasive detection of Alzheimer’s disease and related dementias using a large-scale multilingual voice dataset and language-agnostic AI models that analyze vocal biomarkers without relying on speech transcription.
BACKGROUND:
Early detection of Alzheimer’s disease and related dementias (ADRD) remains...
Published: 6/19/2026
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Inventor(s): Wei Bo, Wenyao Xu, Aditya Challamarad, Harry Lin
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Diagnostics
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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties
BACKGROUND:
The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 6/19/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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