Method and Apparatus for Simultaneous Acquisition of Electrocardiogram Signals and Electrical Impedance Tomography Data
A new imaging technology that can be used with an electrocardiogram to aid the diagnosis and treatment of cardiac and pulmonary conditions.
Background:
Electrical impedance tomography (EIT) is a new imaging technology that can be used with an electrocardiogram (EKG) to aid the diagnosis and treatment of cardiac and pulmonary conditions. Examples...
Published: 10/29/2025
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Inventor(s): Gary Saulnier, Ahmed Abdelwahab, Omid Rajabi Shishvan, Nilton Barbosa da Rosa
Keywords(s): electrical impedance tomography, electrocardiogram, heart/lung function, medical equipment, medical imaging, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging
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Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics
This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications.
Background:
There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...
Published: 10/24/2025
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Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Bioinformatics, Technology Classifications > Artificial Intelligence, Technology Classifications > Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Dental
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In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses
This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases.
Background:
In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 10/29/2025
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Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses.
Background:
Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Lifeng Zhou
Keywords(s): DNA, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
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Ribonuclease-responsive DNA Nanoswitches
A DNA nanoswitch that provides a simple mix-and-read methodology to detect RNases (ribonucleases) in a biological sample.
Background: RNases are involved in many biological processes including neurotoxicity, genome replication and maintenance, immune-suppression, and antitumor activity. RNase inhibitors are also potential drug candidates and biomarkers...
Published: 10/24/2025
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Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): DNA, RNA, RNA-switch
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents, Technology Classifications > Diagnostics
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DsDNA-templated Substrates as Fluorescent Probes for CRISPR-Cas12a-based Diagnostics
New design for CRISPR-based fluorescent probes improves disease diagnostics and sensing. Background: Scientists use the naturally occurring CRISPR-Cas12a gene editing system as a valuable tool for disease diagnostics. When Cas12a finds its target -- a sequence of double-stranded DNA -- it cuts it. In the process, it also cuts other nearby DNAs. Scientists...
Published: 10/24/2025
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Inventor(s): Mehmet Yigit, Christopher Smith
Keywords(s): agriculture, biotechnology, Cas12a, Cas12a, CRISPR, CRISPR, detection, detection, DNA, DNA, fluorescence, fluorescence, RNA, RNA, sensor, sensor
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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Profiling Chemically Modified DNA/RNA Units for Disease and Cancer Diagnosis
Diagnose a wide variety of conditions by analyzing DNA and RNA nucleotides/nucleosides. Background: In theory, RNA and DNA can be used to diagnose a broad range of diseases. Unfortunately, there are no existing technologies capable of providing comprehensive profiles of variant DNA/RNA components. Established approaches for the analysis/detection of...
Published: 10/24/2025
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Inventor(s): Daniele Fabris, Rebecca Rose
Keywords(s): cancer, DNA modifications, epigenetics, genome-wide analysis, infection, oncology, RNA modifications, Technologies
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
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Glycosyltransferase Mutation-Activity Landscape
A streamlined high-throughput platform for engineering glycosyltransferases and glucosidases
Background:
Glycosyltransferases are enzymes that commonly transfer monosaccharides to proteins and lipid scaffolds. These enzymes constitute ~2% of the coding human genome, representing over 200 proteins. Mutations in glycosyltransferases lead to disease;...
Published: 11/17/2025
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Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Biotechnology, Diagnostic, Featured, Pharmaceutical, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biomedical Science and Engineering
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Machine Learning Diagnosis of In Vivo Tissues by Extracting Tissue-Energy Characteristic Features from Non-Invasively Acquired Computed Tomographic Data
The technology features enable ML models to more accurately classify indeterminate pulmonary nodules and colorectal polyps
Background:
Computed tomography (CT) is a widely used imaging tool for early detection of cancers such as lung and colorectal cancer. However, current low-dose CT screening protocols suffer from high false positive rates, particularly...
Published: 9/19/2025
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Inventor(s): Jerome Liang
Keywords(s):
Category(s): Technology Classifications > Artificial Intelligence, Technology Classifications > Computer Software, Technology Classifications > Diagnostics, Technology Classifications > Healthcare IT, Technology Classifications > Information Technology, Technology Classifications > Medical Imaging, Campus > Stony Brook University
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Dual isotope labeled Alanines as imaging agents for chronic diseases detection
Novel PET tracers for detecting chronic diseases with improved specificity for detecting bacterial infection
Background:
Positron emission tomography (PET) is a non-invasive, functional imaging technique that is used to monitor metabolic processes and diagnose diseases including cancer and bacterial infections. Fluorodeoxyglucose (FDG) is the most...
Published: 10/6/2025
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Inventor(s): Wenchao Qu, Kaixuan Li, Peter Tonge
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Campus > Stony Brook University
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