Generation of a single-chain recombinant IgA1 isotype antibody compatible with in vivo nucleic acid delivery for the treatment and prevention of flavivirus infection
This technology uses a single-chain IgA1 antibody delivered by DNA or RNA to enable the body to produce its own protection against dengue and Zika viruses, offering rapid, safe, and scalable prevention and treatment without risk of antibody-dependent enhancement.
Background:
Flavivirus infections, including those caused by dengue and Zika viruses,...
Published: 2/6/2026
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Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): antibody therapy, infectious diseases, nucleic acid, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
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Use of recombinant IgA1 isotype mAbs to prevent and antagonize transplacental transmission of flaviviruses in pregnant women
This technology is a single-chain IgA1 antibody delivered by DNA or RNA, enabling the body to produce its own dengue-neutralizing antibodies safely and quickly, without the risk of worsening infection, for rapid prevention and treatment of flavivirus diseases.
Background:
The field of flavivirus therapeutics, particularly for diseases like dengue,...
Published: 2/6/2026
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Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): infectious diseases, monoclonal antibodies, pregnancy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
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Contact Lens Design
This technology is a novel specialty soft contact lens that helps align the eyes in children with intermittent exotropia type strabismus, while preventing any adverse myopia progression, offering both vision correction and cosmetic improvement without worsening nearsightedness.
Background:
Strabismus, particularly exotropia, is a condition characterized...
Published: 1/29/2026
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Inventor(s): Zi Rui Li
Keywords(s): Technologies
Category(s): Campus > SUNY College of Optometry, Technology Classifications > Healthcare
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Pharmacological strategy to treat hydrocephalus
This technology offers a non-surgical treatment for hydrocephalus by using drugs to enhance the removal of harmful macromolecules from the brain’s ventricles, targeting specific cellular transport mechanisms to reduce fluid buildup and disease progression.
Background:
Hydrocephalus is a neurological disorder characterized by the abnormal accumulation...
Published: 1/29/2026
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Inventor(s): Satish Krishnamurthy, David Lehmann
Keywords(s): hydrocephalus, pharmacology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Polyphasic Ultrasonic Power transfer for wireless charging of implants.
This technology uses multiple piezoelectric transducers with controlled phase shifts to create engineered ultrasonic waves, enabling efficient, wireless power transfer through tissue to implanted medical devices or sensors, overcoming limitations of traditional electromagnetic intra-body power transfer systems.
Background:
Wireless power transfer...
Published: 1/29/2026
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Inventor(s): Amit Sangwan, Dante Riccoboni
Keywords(s): bioelectronics, biomedical engineering, biotechnology, Medical Device, Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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“Smart” Electronic Rotating Hemostatic Valve and Tuohy-Borst Adapter with Integrated Activation and Force Sensors with Interface with Heads-Up Electronic Displays and Cloud-Based Data Analysis To Optimize Technical Safety, Display Live Quantified Operator Variables and Inform Individualized Procedural Technique
This technology measures, records, and displays force measurements exerted on catheters, providing valuable data to improve patient outcomes.
Background:
Rotating hemostatic valves (RHV) and Tuohy-Borst adapters (TBA) are used with catheter-based and other relevant procedures. Currently available RHVs and TBAs lack integrated sensors to provide feedback...
Published: 1/29/2026
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Inventor(s): Hesham Masoud, Andrew Decker
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 1/29/2026
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Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
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Modifying Angiogenic Sprouting Using Pulsed Electromagnetic Fields (PEMF)
A novel method for the treatment of chronic wounds based on amplitude-modulated pulsed electromagnetic fields (PEMFs).
Background:
Chronic wounds adversely impact the quality of life and health of patients and their families, due to pain, anxiety, loss of function, loss of mobility, depression, shame, and social isolation. Wound healing requires...
Published: 1/29/2026
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Inventor(s): Linghong Li, Wayne Patton
Keywords(s): angiogenic sprouting, autophagy-lysosomal pathway, cytoplasmic granulation, electromagnetic field, ion cyclotron resonance, sprouting, Technologies
Category(s): Campus > SUNY Potsdam, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
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Method and Apparatus for Simultaneous Acquisition of Electrocardiogram Signals and Electrical Impedance Tomography Data
A new imaging technology that can be used with an electrocardiogram to aid the diagnosis and treatment of cardiac and pulmonary conditions.
Background:
Electrical impedance tomography (EIT) is a new imaging technology that can be used with an electrocardiogram (EKG) to aid the diagnosis and treatment of cardiac and pulmonary conditions. Examples...
Published: 1/29/2026
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Inventor(s): Gary Saulnier, Ahmed Abdelwahab, Omid Rajabi Shishvan, Nilton Barbosa da Rosa
Keywords(s): electrical impedance tomography, electrocardiogram, heart/lung function, medical equipment, medical imaging, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging
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Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics
This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications.
Background:
There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...
Published: 1/29/2026
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Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Bioinformatics, Technology Classifications > Artificial Intelligence, Technology Classifications > Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Dental
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