Developing a new mechanism-based method to treat behavioral variant frontotemporal dementia
This technology offers a novel, mechanism-based therapeutic method using oxytocin and specific compounds to treat social-affective deficits in behavioral variant frontotemporal dementia (bvFTD).
Background:
Behavioral variant frontotemporal dementia (bvFTD) is a prevalent form of dementia characterized by severe social and emotional impairments,...
Published: 3/30/2026
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Inventor(s): Wei-Dong Yao
Keywords(s): dementia, electrophysiology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness.
Background:
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026
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Inventor(s): Yamin Li, Yuqin Men, Qinghe Meng, Robert Cooney
Keywords(s): anti-inflammatory therapeutic, drug delivery, lipids, mRNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 3/18/2026
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Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
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Diabetic Foot Examiner
This technology enables diabetic patients to detect foot ulcers easily and effectively at home.
Background:
Diabetic foot ulcers are a significant health problem (15% baseline probability) in the growing diabetic population. Foot ulcers can become infected and lead to hospitalization or even amputation. The best way to address this disease is through...
Published: 3/13/2026
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Inventor(s): Ronald Miller
Keywords(s): artificial intelligence, diabetes, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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3D-Printed Theranostic Dose Caddy
This technology enables safer administration of radioligand therapies, allowing for healthier, lower radiation doses to both patients and administering staff.
Background:
At present, there are two FDA-approved radioligand therapies for broad use in cancer treatment: Lutathera (177Lutetium DOTATATE) and Pluvicto (177Lutetium Vipivotide Tetraxetan)....
Published: 3/13/2026
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Inventor(s): David Lubin, David Feiglin, Kurtis Wilson, Leen Alkukhun, Garrett Depalma, Kent Ogden, Mary McGrath, Paul Depew, Zohaib Khan, Meghan Stanton
Keywords(s): 3D printing, cancer therapy, radiology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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Modular Hybrid Simulator (Endovascular Flow model with embedded sensors for operative feedback) powered by 3D auto segmentation software for Endovascular Modeling and Flow Model additions.
The Modular Hybrid Simulator is an advanced training platform for endovascular procedures, combining patient-specific 3D modeling with real-time operative feedback to enhance learning and procedural planning.
Background:
Endovascular training currently faces challenges such as inconsistent learning curves among trainees and the limitations of existing...
Published: 3/3/2026
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Inventor(s): Hesham Masoud
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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Ultrasonic Transmission System with Modular Cavitation-Enhancing Wire
This device uses ultrasonic vibrations delivered through a specialized wire to safely and efficiently clear blockages or remove implants from medical tubes, offering a non-invasive, customizable solution for maintaining and treating tube obstructions in healthcare settings.
Background:
Nephrostomy tubes and other indwelling medical devices are critical...
Published: 3/26/2026
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Inventor(s): Alexander Collins, Scott Wiener
Keywords(s): modular instrument, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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Integrating AI in Back Injury Prevention
This wearable technology integrates sensors into a back brace and shoe inserts to monitor posture and movement. Using AI-driven analysis, it provides real-time feedback via a software application, helping Direct Care Workers prevent the risk of back injuries during lifting and transfer tasks.
Background:
Workplace injuries, particularly musculoskeletal...
Published: 2/25/2026
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Inventor(s): Yuchi Young
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Artificial Intelligence, Technology Classifications > Healthcare
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Generation of a single-chain recombinant IgA1 isotype antibody compatible with in vivo nucleic acid delivery for the treatment and prevention of flavivirus infection
This technology uses a single-chain IgA1 antibody delivered by DNA or RNA to enable the body to produce its own protection against dengue and Zika viruses, offering rapid, safe, and scalable prevention and treatment without risk of antibody-dependent enhancement.
Background:
Flavivirus infections, including those caused by dengue and Zika viruses,...
Published: 3/18/2026
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Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): antibody therapy, infectious diseases, nucleic acid, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
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Use of recombinant IgA1 isotype mAbs to prevent and antagonize transplacental transmission of flaviviruses in pregnant women
This technology is a single-chain IgA1 antibody delivered by DNA or RNA, enabling the body to produce its own dengue-neutralizing antibodies safely and quickly, without the risk of worsening infection, for rapid prevention and treatment of flavivirus diseases.
Background:
The field of flavivirus therapeutics, particularly for diseases like dengue,...
Published: 3/18/2026
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Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): infectious diseases, monoclonal antibodies, pregnancy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
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