Method and Apparatus for Simultaneous Acquisition of Electrocardiogram Signals and Electrical Impedance Tomography Data
A new imaging technology that can be used with an electrocardiogram to aid the diagnosis and treatment of cardiac and pulmonary conditions.
Background:
Electrical impedance tomography (EIT) is a new imaging technology that can be used with an electrocardiogram (EKG) to aid the diagnosis and treatment of cardiac and pulmonary conditions. Examples...
Published: 4/1/2025
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Inventor(s): Gary Saulnier, Ahmed Abdelwahab, Omid Rajabi Shishvan, Nilton Barbosa da Rosa
Keywords(s): electrical impedance tomography, electrocardiogram, heart/lung function, medical equipment, medical imaging, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging
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RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes.
Background:
Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 4/1/2025
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Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses
This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases.
Background:
In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 4/1/2025
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Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity.
Background:
Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 4/1/2025
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Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
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Discovery of Novel SHIP1 Agonists
A new class of SHIP1 agonists that offer the potential for the development of new treatments for a variety of diseases.
Background:
An agonist is a drug or substance that binds to a cell receptor, producing the same action as the substance that would naturally bind to the receptor. Agonists form the basis for a wide variety of therapeutics. The...
Published: 4/1/2025
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Inventor(s): William Kerr, Sandra Denney
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Artificial Intelligence, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity
An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva.
Background:
Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 4/1/2025
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Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)
Offers the potential of real-time small-sample analysis for a very large variety of applications.
Background:
Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....
Published: 4/1/2025
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Inventor(s): Rabi Musah
Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Environment, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents
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Algorithm for Identifying Images of Fluorescently-Labeled Cells
Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more.
Background:
Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...
Published: 4/1/2025
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Inventor(s): Alex Valm, Yunlong Feng
Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Viral Vectors
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Injectable Nanogel for Immune Modulation Therapy
A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis.
Background:
Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 4/1/2025
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Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium
Produces cyclic peptide libraries quickly, cheaply, and without the need of purification.
Background:
Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...
Published: 4/1/2025
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Inventor(s): Qiang Zhang, Huan Chen
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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