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Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease

Repurposed antidepressant agents for treating levodopa-induced dyskinesia in Parkinson's disease Background: Dopamine replacement therapy with L-DOPA remains the gold-standard treatment for the crippling movement disruptions affecting >10 million Parkinson’s Disease patients worldwide. However, L-DOPA therapies, especially after...
Published: 10/16/2020   |   Inventor(s): Christopher Bishop
Keywords(s):  
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Robotic Gripper with Variable Stiffness Actuators

A robotic gripper with variable stiffness actuators improves the safety and robustness of the grasp and enhances dynamic manipulation. Background:The reliable grasping and handling of objects is essential to industrial and service robots for physical human-robot interaction (pHRI). Moreover, safety becomes an important issue when a robot needs to handle...
Published: 10/12/2020   |   Inventor(s): Ehsan Esfahani, Amirhossein Hajiagha Memar
Keywords(s): Assistive Technology, Robotics, Technologies
Category(s): Technology Classifications > Engineering, Technology Classifications > Assistive Technology, Technology Classifications > Healthcare, Campus > University at Buffalo

Skin Graft Suture Device

A suturing device with sewing machine-like action for rapid skin graft quilting using absorbable thread with bristles or tines. The prototype has been used to carry out challenging urinary reconstruction skin grafts in 30 seconds. Additional applications include plastic surgery for burn victims, hernia repair, and battlefield surgery. Patent Pending...
Published: 9/17/2020   |   Inventor(s): Dmitriy Nikolavsky, Gennady Bratslavsky
Keywords(s): #SUNYresearch, barbed suture, healthcare, medical devices, surgery, suturing technique, Technologies
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare, Campus > Upstate Medical University

Proprietary Doxorubicin Formulation Increases Survival and Safety Over Free Doxorubicin and Doxil

Doxorubicin (DOX) is a commonly used anticancer chemo drug, and its clinical use is associated with dose-limiting cardiotoxicity. It is used to treat a wide variety of cancers including leukemia, bone and Karposi sarcomas, multiple myeloma, and ovarian, breast, kidney, endometrial, liver and gastric cancers. Despite being a generic, the market for liposomal...
Published: 9/17/2020   |   Inventor(s): Juntao Luo, Dandan Guo, Changying Shi
Keywords(s): #SUNYresearch, Featured, Technologies
Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University

Biomarker Diagnostic for Crohn's Disease Severity

There are approximately 1.8 million people suffering from Crohn's disease in the US and Europe. A portion of these will require aggressive treatment, such as surgical resections and biologics. Upstate has identified a novel mutant fusion mRNA that allows easy and definitive identification of a subset of Crohn's Disease patients that is highly likely...
Published: 9/17/2020   |   Inventor(s): William Kerr, Frank Middleton, Sandra Denney
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University

6-Mer Peptide for Anti-Cancer Therapeutic Use

A 6-mer peptide (Win6mer) has been designed which has potential as an anti-cancer therapeutic. The Win6mer disrupts MLL1 and SETd1A core complex assembly, but does not inhibit isolated SET domain activity. MLL I belongs to the SETI family of histone H3 lysine 4 (H3K4) methyltransferases, comprised of MLLl-4 and SETdlA/B. MLLl translocations are present...
Published: 9/17/2020   |   Inventor(s): Michael Cosgrove, Nilda Alicea-Velazquez, Stephen Shinsky
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University

A constituent purified from plant Arctium Lappa L as a novel cancer therapeutic

In the United States there were more than 1.5 million new diagnosed cancer cases, and approximately 577,000 cancer-related deaths in the U.S. in 2012, according to the American Cancer Society. The development and discovery of newer anticancer therapeutics are still urgently needed. For the past four decades, cancer treatments have commonly been derived...
Published: 9/17/2020   |   Inventor(s): Ying Huang, Qing Sun, M. Sheikh
Keywords(s): anticancer therapeutic, natural product extract
Category(s): Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

Internet-based Psychoeducational Program for Women with Breast Cancer

A personalized and self-guided web-based, psychoeducational program that offers women a place to turn in the initial weeks to months following breast cancer diagnosis.CaringGuidance(TM) is an internet-based educational and support site for women recently diagnosed with breast cancer. Caring Guidance (TM) offers an interactive, self-guided program that...
Published: 3/23/2020   |   Inventor(s): Robin Lally
Keywords(s): Technologies
Category(s): Technology Classifications > Education and Training, Technology Classifications > Healthcare, Campus > University at Buffalo

Traverse Biosciences, Inc.

Traverse Biosciences is commercializing novel drug candidates for the treatment of inflammatory diseases and related conditions affecting humans and companion animals. www.traversebiosciences.com
Published: 9/26/2019   |   Inventor(s): Stony Brook University
Keywords(s): Startups
Category(s): Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Campus > Stony Brook University

miR Scientific, LLC

With the goal of transforming cancer management, miR Scientific has developed non-invasive liquid biopsy urine tests. These tests are accurate in monitoring prostate and bladder cancers to work toward life changing interventions. www.mirscientific.com
Published: 9/26/2019   |   Inventor(s): University at Albany
Keywords(s): Startups
Category(s): Technology Classifications > Healthcare, Technology Classifications > Medical Devices, Campus > University at Albany
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