Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity.
Background:
Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 5/13/2025
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Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
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Suspended Graphene Energy Harvesting Solid State Structure
An energy harvesting device made possible by the oscillatory behavior of suspending graphene.
Background:
Even low power devices need consistent, reliable energy sources that in most cases must be powered indefinitely in order to accomplish the device’s objectives. Maintaining a secure and independent energy source for powering small, sometimes...
Published: 5/13/2025
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Inventor(s): Nicholas Pieniazek, Christopher Hobbs, Vincent LaBella
Keywords(s): battery systems, circuit design, energy storage devices, material science, microsystem, nanoengineering, nanofabrication, nanotechnology, semiconductors, Technologies
Category(s): Technology Classifications > Energy, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Campus > SUNY Polytechnic Institute, Campus > NY CREATES
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A Nanotrap to Improve Survival in Severe Sepsis by Attenuating Hyperinflammation Through Hemoperfusion
This optimized nanotrap therapy in combination with a moderate antibiotic treatment resulted in a 100% survival rate in severe septic mice.
Background:
The mortality rates in severe sepsis patients are 30‑41%. In the U.S. alone, 1.7 million people develop sepsis on a yearly basis. Effective therapies to prevent or treat the cytokine storm or septic...
Published: 5/13/2025
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Inventor(s): Juntao Luo, Lili Wang, Changying Shi
Keywords(s):
Category(s): Campus > Upstate Medical University, Technology Classifications > Nanotechnology
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Telodendrimer Nanoparticles for Protein Delivery
A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics.
Background:
Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...
Published: 5/13/2025
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Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall
Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
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Improved Chemical-Mechanical Polishing Slurry Composition and Method to Improve Polishing of Metals and Non-metals Using Cerium Oxide Nanoparticles
Reducing manufacturing time, cost, and labor by employing chemistry to transform a two-step process into an easily controlled single-step.
Background: Integrated circuits are built of many layers. Each layer must be perfectly flat so that connections line up between layers and electricity flows properly throughout. Conventional CMP systems consist...
Published: 5/13/2025
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Inventor(s): Christopher Netzband, Kathleen Dunn
Keywords(s): abrasive, cerium, cerium oxide, chemical activity, chemical mechanical polishing, CMP, CMP slurries, dielectrics, fiber optics, integrated circuit, lens, mechanical polish, metallic surface, optics, polish, polishing, semiconductor wafers, semiconductors, slurry, surface finishing, surface quality
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
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Deuterized Low-K Dielectric Materials for TDDB Mitigation
Simple, scalable and inexpensive process to replace the hydrogen in low-k dielectrics with deuterium to improve semiconductor performance. Background: Low-k dielectrics are a class of materials used in the manufacture of nanoscale semiconductor devices. The problem with low-k dielectrics is that they are susceptible to a phenomenon known as time dependent...
Published: 5/13/2025
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Inventor(s): James Lloyd, Patrick Lenahan, Niaz Mahmud
Keywords(s): nanotechnology, semiconductors
Category(s): Technology Classifications > Nanotechnology, Campus > SUNY Polytechnic Institute
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Hydrogel Tubular Structures for Cell Culture and Organoid Growth
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A device and tunable process to produce alginate hydrogel tubular structures in various configurations for 3D tissue culture
Background:
Three-dimensional (3D) cell culture is a powerful research tool for recapitulating in vivo conditions and morphology. Despite increasing...
Published: 5/13/2025
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Inventor(s): Yubing Xie, Sujith Kollampally, Matthew Jorgensen
Keywords(s): #SUNYresearch, material science, microsystem, nanotechnology, Technologies
Category(s): Technology Classifications > Nanotechnology, Campus > University at Albany
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Gate All-Around Field Effect Transistors Including Quantum-Based Features
A device that increases computational processing power in a single Gate All-Around Field Effect Transistor including quantum-based features. Background: A major problem with conventional transistor technology is that conventional MOSFETs are ill equipped to implement multivalued logic. As the number of states a transistor can store increases, the number...
Published: 5/13/2025
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Inventor(s): Supriyo Karmakar
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Nanotechnology, Campus > Farmingdale State College
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Metal-Insulator-Metal Selector Device for Resistive Memory Based on Sub-Band Conduction in Large Band-Gap Insulators
A new selector device that contains no toxic materials and is ideal for use in applications requiring ultra-dense memory, such as AI and ML. Background: Selector devices play an important role in ultra-dense memory -- the powerful memory arrays used in applications such as artificial intelligence and machine learning. The two-terminal selector devices...
Published: 5/13/2025
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Inventor(s): Nathaniel Cady, Karsten Beckmann
Keywords(s):
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Electronics, Technology Classifications > Nanotechnology
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System and Methods for Detecting, Capturing, and Measuring Nanoparticles
Speeds the semiconductor manufacturing process by detecting particles smaller than 20nm before they have adhered to the silicon wafer.
Background:
The conventional method for of detecting particles during the semiconductor manufacturing process occurs only after the particles have adhered to silicon wafer. While that approach is easier because...
Published: 5/13/2025
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Inventor(s): Gregory Denbeaux, Yashdeep Khopkar
Keywords(s): defect-tolerant semiconductor, Technologies
Category(s): Technology Classifications > Nanotechnology, Campus, Campus > SUNY Polytechnic Institute
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