Targeted Immune-Activating Antibody Conjugates for Cancer and Infectious Disease Therapy
This technology enables precise activation of the immune system by delivering potent TLR7/8 agonists directly to diseased cells. By combining immune stimulators with antibody targeting, it enhances therapeutic impact while minimizing systemic side effects. The approach offers a safer and more effective way to treat cancer and infectious diseases by...
Published: 2/3/2026
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Inventor(s): Lawrence Tumey, Emmanuel Olawode
Keywords(s): Technologies, XCEED
Category(s): Campus > Binghamton University, Technology Classifications > Biomedical Science and Engineering
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Novel three-dimensional, conformal microelectrode arrays for interrogating and manipulating three-dimensional cell culture systems
A flexible, biocompatible microelectrode array wraps around 3D cell cultures such as organoids, enabling comprehensive electrical recording and stimulation for advanced research, drug testing, and personalized medicine, overcoming the limitations of traditional flat electrode arrays.
Background:
Three-dimensional (3D) cell culture systems, such as...
Published: 1/29/2026
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Inventor(s): Susan Sharfstein, Nathaniel Cady, Yubing Xie, Natalya Tokranova, Anthony Manning, Fernando Pesantez Torres
Keywords(s): 3D culture, 3D flexible microelectrode, electrophysiology, microelectrode array, microfabrication, neurodegeneration, organoid, polymer materials, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
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Pharmacological strategy to treat hydrocephalus
This technology offers a non-surgical treatment for hydrocephalus by using drugs to enhance the removal of harmful macromolecules from the brain’s ventricles, targeting specific cellular transport mechanisms to reduce fluid buildup and disease progression.
Background:
Hydrocephalus is a neurological disorder characterized by the abnormal accumulation...
Published: 1/29/2026
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Inventor(s): Satish Krishnamurthy, David Lehmann
Keywords(s): hydrocephalus, pharmacology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Polyphasic Ultrasonic Power transfer for wireless charging of implants.
This technology uses multiple piezoelectric transducers with controlled phase shifts to create engineered ultrasonic waves, enabling efficient, wireless power transfer through tissue to implanted medical devices or sensors, overcoming limitations of traditional electromagnetic intra-body power transfer systems.
Background:
Wireless power transfer...
Published: 1/29/2026
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Inventor(s): Amit Sangwan, Dante Riccoboni
Keywords(s): bioelectronics, biomedical engineering, biotechnology, Medical Device, Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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High-Density Neurostimulation System
High-density cluster electrode technology that enables a high degree of scalability and customization for neurostimulation applications.
Background:
Existing skin-surface neurostimulation is achieved by a single electrode that performs bulk stimulation on the entire tissue in the neurostimulation area. It does not have the capability to control the...
Published: 2/3/2026
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Inventor(s): Filip Stefanovic, Albert Titus
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Assistive Technology, Technology Classifications > Medical Devices
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“Smart” Electronic Rotating Hemostatic Valve and Tuohy-Borst Adapter with Integrated Activation and Force Sensors with Interface with Heads-Up Electronic Displays and Cloud-Based Data Analysis To Optimize Technical Safety, Display Live Quantified Operator Variables and Inform Individualized Procedural Technique
This technology measures, records, and displays force measurements exerted on catheters, providing valuable data to improve patient outcomes.
Background:
Rotating hemostatic valves (RHV) and Tuohy-Borst adapters (TBA) are used with catheter-based and other relevant procedures. Currently available RHVs and TBAs lack integrated sensors to provide feedback...
Published: 1/29/2026
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Inventor(s): Hesham Masoud, Andrew Decker
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 1/29/2026
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Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
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Rapid, robust, and near point-of-care saliva-based nucleic acid detection of dengue virus infections
This technology enables rapid, non-invasive detection and differentiation of all four dengue virus serotypes using saliva samples, with advanced qPCR and RT-LAMP assays, making dengue diagnosis easier, faster, and more accessible without the need for blood draws.
Background:
Dengue virus (DENV) is a major global health concern, with hundreds of millions...
Published: 1/29/2026
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Inventor(s): Frank Middleton, Stephen Thomas, Adam Waickman, Timothy Rooney
Keywords(s): diagnostics, disease diagnosis, isothermal amplification (LAMP), nucleic acid, PCR, RNA viruses, saliva, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Screens and Assays, Technology Classifications > Biomedical Science and Engineering
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Sulfonium Lipid Nanoparticles for Intranasal mRNA Delivery to Lung Epithelial and Immune Cells
This technology uses specially designed sulfonium lipid nanoparticles to deliver mRNA directly to lung cells through the nose, offering a non-invasive, more effective and targeted treatment for pulmonary diseases like asthma and cystic fibrosis.
Background:
The field of pulmonary medicine faces significant challenges in the treatment of diseases...
Published: 1/29/2026
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Inventor(s): Yamin Li, Yuqin Men
Keywords(s): active pharmaceutical ingredient, chemicals, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery
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Therapeutic backbone and scaffold modification in the physiological environment
This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications.
Background:
Proteins and polypeptides play a central role...
Published: 1/29/2026
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Inventor(s): Qiang Zhang
Keywords(s): antibody therapy, GLP-1 secretion, Insulin, protein engineering, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
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