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Adapter Couples Self-Retaining Surgical Retractor with Hand-Held Retractors

​An adapter that expedites bone surgery by making hand-held retractors self-retaining. Background: Orthopedic surgeons require unfettered access to exposed bone. That means keeping the skin, subcutaneous fat, tissues, and muscles out of the way with retractors. Currently, there are two common types of retractors for this purpose—self-retaining...
Published: 5/7/2024   |   Inventor(s): Timothy Damron
Keywords(s): bone, Homann, retractor, self-retaining, Weitlaner
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices

Drill Guide/Suture Passer for Posterior Approach Total Hip Soft Tissue Repair

­Combined drill guide and suture passer for use in assisting repair following posterior approach total hip arthroplasty. Background: The posterior approach to the hip for total hip replacement as well as trauma, pediatric orthopedic surgery, and tumors is the most common approach for total hip arthroplasties. However, the performance of this...
Published: 5/1/2024   |   Inventor(s): Timothy Damron
Keywords(s): biomedical engineering, biotechnology, hardware, healthcare, medical devices, medical equipment, orthopedics, surgery, suturing technique, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Devices

DUB Biologics

­https://www.linkedin.com/company/dub-biologics/ https://www.linkedin.com/company/dub-biologics/ https://suny.technologypublisher.com/files/sites/dub_biologics.png https://suny.technologypublisher.com/files/sites/dub_biologics.png
Published: 3/11/2024   |   Inventor(s):  
Keywords(s): Startups
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering

Tibial Tubercle Osteotomy Fixation Device

Fixation device to secure bone fragment of tibial tuberosity to native bone after osteotomy surgical procedure. Background: Standard osteotomy techniques to join the tibial tubercle fragment to native bone include screw fixation alone or fixation with wire or suture, which are not reliable methods to holding the bone in place to avoid displacement...
Published: 5/7/2024   |   Inventor(s): Timothy Damron
Keywords(s): biomedical, biomedical engineering, hardware, healthcare, instrumentation, medical devices, medical equipment, orthopedics, osteoarthritis, surgery, suturing technique, Technologies
Category(s): Technology Classifications > Medical Devices, Campus > Upstate Medical University

Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care

A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background: Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 4/3/2024   |   Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines

Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery

A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity. Background: Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 6/21/2024   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines

Discovery of Novel SHIP1 Agonists

A new class of SHIP1 agonists that offer the potential for the development of new treatments for a variety of diseases. Background: An agonist is a drug or substance that binds to a cell receptor, producing the same action as the substance that would naturally bind to the receptor. Agonists form the basis for a wide variety of therapeutics. The...
Published: 5/10/2024   |   Inventor(s): William Kerr, Sandra Denney
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Artificial Intelligence, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Purification of Human β and γ Actin from Budding Yeast

Provides easily accessible and relatively abundant sources of human β- or γ-actin. Background: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. In vertebrates, three main groups of actin isoforms (alpha, beta and gamma) have been identified. Alpha actins...
Published: 7/24/2023   |   Inventor(s): David Amberg, Brian Haarer, Jessica Henty-Ridilla
Keywords(s): cytoplasmic actin, non-muscle actin, Technologies, β-actin, γ-actin
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents

Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity

An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva. Background: Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 4/3/2024   |   Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines

Injectable Nanogel for Immune Modulation Therapy

A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis. Background: Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 11/7/2024   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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