Decision Support Tool for Detection of Prostate Lesions on MRI
Prostate cancer diagnostic software that provides expert-level lesion detection, localization, automated segmentation, and automated report generation in less than 45 seconds.
Background:
According to the American Cancer Society, about 1 in 8 men will be diagnosed with prostate cancer during their lifetime. American Urologic Association guidelines...
Published: 9/25/2025
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Inventor(s): Thomas Sanford, Gennady Bratslavsky
Keywords(s): magnetic resonance imaging, oncology, prostate, software, Technologies
Category(s): Technology Classifications > Healthcare IT, Campus > Upstate Medical University
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Netrin-4–Mediated Disruption of Basement Membranes for Targeted Therapeutic Delivery
Novel tools that promote the delivery of therapeutics to treat inner retinal diseases such as diabetic retinopathy, retinal vein occlusion, and retinitis pigmentosa.
Background:
Non-surgical access to tissues for direct biological manipulation, e.g. gene transfer, stem cell transplantation, and drug delivery, can be difficult because many tissues...
Published: 6/16/2025
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Inventor(s): Dale Hunter, William Brunken, Peter Yurchenco, Karen Mckee
Keywords(s): biologic therapies, drug delivery component, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines
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Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care
A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background:
Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 5/13/2025
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Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines
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Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity.
Background:
Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 5/13/2025
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Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
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Discovery of Novel SHIP1 Agonists
A new class of SHIP1 agonists that offer the potential for the development of new treatments for a variety of diseases.
Background:
An agonist is a drug or substance that binds to a cell receptor, producing the same action as the substance that would naturally bind to the receptor. Agonists form the basis for a wide variety of therapeutics. The...
Published: 5/13/2025
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Inventor(s): William Kerr, Robert Anderson, John Chisholm, Sandra Denney, Shea Meyer, Angela Pacherille
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Artificial Intelligence, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare
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Purification of Human β and γ Actin from Budding Yeast
Provides easily accessible and relatively abundant sources of human β- or γ-actin.
Background:
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. In vertebrates, three main groups of actin isoforms (alpha, beta and gamma) have been identified. Alpha actins...
Published: 9/4/2025
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Inventor(s): David Amberg, Brian Haarer, Jessica Henty-Ridilla
Keywords(s): cytoplasmic actin, non-muscle actin, Technologies, β-actin, γ-actin
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Research Tools and Reagents
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Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity
An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva.
Background:
Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 5/13/2025
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Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Injectable Nanogel for Immune Modulation Therapy
A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis.
Background:
Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 5/13/2025
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Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
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Stratification Method that Determines the Prognosis of Breast Cancer at a Personalized Level
A reliable, accurate, and versatile method for determining the prognosis of primary breast cancer tumors post-surgery.
Background:
Breast cancer is the second most common type of cancer in women in the United States, after skin cancer. On rare occasions, it can also occur in men. According to the American Cancer Society, nearly 300,000 new cases...
Published: 5/13/2025
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Inventor(s): Vladimir Kuznetsov, Leszek Kotula
Keywords(s): biomarkers, biostatistics, breast cancer, diagnostics, functional genomics, gene expression analysis, oncology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
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Balloon Assisted Thrombectomy Dual Aspiration and Distal Access Catheter System for Neurovascular Thrombectomy and Intracranial Emboli Protection
Improves the treatment of acute ischemic stroke by reducing the risk of distal thromboembolism and intercranial emboli.
Background:
Large vessel occlusion accounts for 30% of acute ischemic stroke (AIS) and is a major cause of devastating neurologic deficits. A large vessel occlusion (LVO) occurs when a large blood vessel carrying oxygen and nutrients...
Published: 5/13/2025
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Inventor(s): Hesham Masoud
Keywords(s): medical devices, Technologies
Category(s): Technology Classifications > Medical Devices, Campus > Upstate Medical University
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