Bioprinting of collagenous bioinks
050-9518 Rapidly Synthesized Extracellular Matrix-Based Gels and Patterning Techniques, from Micro- to Macro-Scale/Bioprinting of Collagenous Bioinks
A method for bioprinting physiological materials, enabling rapid and precise 3D patterning of structures
Background:
Biological tissues are characterized by intricate 3D patterns of cells and extracellular...
Published: 2/27/2026
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Inventor(s): Michael Mak
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Campus > Stony Brook University
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Rapid, robust, and near point-of-care saliva-based nucleic acid detection of dengue virus infections
This technology enables rapid, non-invasive detection and differentiation of all four dengue virus serotypes using saliva samples, with advanced qPCR and RT-LAMP assays, making dengue diagnosis easier, faster, and more accessible without the need for blood draws.
Background:
Dengue virus (DENV) is a major global health concern, with hundreds of millions...
Published: 2/17/2026
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Inventor(s): Frank Middleton, Stephen Thomas, Adam Waickman, Timothy Rooney
Keywords(s): diagnostics, disease diagnosis, isothermal amplification (LAMP), nucleic acid, PCR, RNA viruses, saliva, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Screens and Assays, Technology Classifications > Biomedical Science and Engineering
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Method to Determine Quality of Mitochondrial Cargo in Extracellular Vesicles
A novel method that measures mitochondrial membrane potential in extracellular vesicles, providing a direct readout of mitochondrial quality and utility.
Background:
Studies have shown that EV-mediated intercellular communication is influenced, at least in part, by the mitochondrial cargo contained within EVs. This highlights the importance of rigorous...
Published: 2/19/2026
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Inventor(s): Barbara Alevriadou, Zahid Manzar, Hans Minderman
Keywords(s): Biotechnology, Diagnostic, Healthcare, Pharmaceutical, Research Tool, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics
This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications.
Background:
There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...
Published: 1/29/2026
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Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Bioinformatics, Technology Classifications > Artificial Intelligence, Technology Classifications > Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Dental
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Glycosyltransferase Mutation-Activity Landscape
A streamlined high-throughput platform for engineering glycosyltransferases and glucosidases
Background:
Glycosyltransferases are enzymes that commonly transfer monosaccharides to proteins and lipid scaffolds. These enzymes constitute ~2% of the coding human genome, representing over 200 proteins. Mutations in glycosyltransferases lead to disease;...
Published: 2/19/2026
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Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Biotechnology, Diagnostic, Featured, Pharmaceutical, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biomedical Science and Engineering
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Virus-Like Particles for mRNA Delivery
Virus-like particles have been engineered for drug delivery, gene editing applications, mRNA delivery and overcoming barriers in mouse lungs.
Background:
Recent biomedical research has shown increased interest in the use of virus-like particles as a drug delivery vehicle. Current viral vectors have been shown to cause adverse immunological responses,...
Published: 2/19/2026
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Inventor(s): Sriram Neelamegham, Qi Yang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Gene Therapy, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Luminescent Biosensor for Detection of Specific Nucleotide Sequences, Small Molecules, and Proteins at Point-of-Care
A serotonin release assay that requires no special training or expensive equipment, and produces results within hours. Background:
Platelet serotonin release assay (SRA) is a widely-used clinical assay for diagnosing heparin-induced thrombocytopenia (HIT), a life-threatening complication of heparin treatment. The current SRA procedure entails sending...
Published: 1/30/2026
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Inventor(s): Stewart Loh, Harsimranjit Sekhon
Keywords(s): biomarker diagnostics, biosensor, detection, DNA nanoswitches, protein engineering, sensor, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Screens and Assays, Technology Classifications > Therapeutics and Vaccines
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A Rapid, High Content, Reagent Sparing, Fluorescent Plasmonic Assay Platform for Multiplexed Serum Antibody Detection in Lyme Disease and COVID-19
A protein microarray, in the form of a compact biochip, that can be analyzed with high sensitivity using GC-FP technology.
Background:
Some infectious diseases are easy to diagnose, but others are much more difficult. One example is Lyme disease (B. burgdorferi), which is caused by a slow-growing organism that takes many weeks to detect. Current...
Published: 1/30/2026
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Inventor(s): Nathaniel Cady
Keywords(s): antibodies, assays, COVID-19, nanobioscience, nanobiotechnology, screens and assays, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Screens and Assays, Campus > SUNY Polytechnic Institute
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Novel Cryoelectrospun Scaffolds for Tissue Engineering and Methods for Manufacturing
Methods to produce 3D nanofibrous scaffolds that closely mimic soft-tissue stromal ECM using a unique cryoelectrospinning process. Background: The extracellular matrix (ECM) comprising the proteinaceous scaffold within the connective tissue is involved in regulating the function of parenchymal tissue in organs. When that becomes stiff, or fibrotic,...
Published: 1/30/2026
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Inventor(s): Susan Sharfstein, Yubing Xie, Pujhitha Ramesh, James Castracane, Melinda Larsen
Keywords(s): Technologies
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Screens and Assays, Campus > University at Albany
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Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use
" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are diagnosed...
Published: 1/30/2026
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Inventor(s): Li Niu, Zhen Huang
Keywords(s): Technologies
Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Campus, Campus > University at Albany
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