Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties
BACKGROUND:
The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 3/24/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers
BACKGROUND:
There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials.
TECHNOLOGY...
Published: 3/24/2026
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Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
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Bioprinting of collagenous bioinks
050-9518 Rapidly Synthesized Extracellular Matrix-Based Gels and Patterning Techniques, from Micro- to Macro-Scale/Bioprinting of Collagenous Bioinks
A method for bioprinting physiological materials, enabling rapid and precise 3D patterning of structures
Background:
Biological tissues are characterized by intricate 3D patterns of cells and extracellular...
Published: 2/27/2026
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Inventor(s): Michael Mak
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Campus > Stony Brook University
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Ambient-Temperature Direct Air Capture of Carbon Dioxide
Novel amine-based sorbents for carbon dioxide capture with enhanced oxidative and thermal stability
BACKGROUND:
Anthropogenic climate change presents an urgent threat to ecosystems, public health and economic stability. Even single degree increases in global temperatures can trigger irreversible impacts, ranging from biodiversity loss and food insecurity...
Published: 3/3/2026
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Inventor(s): Miao Yu, Kaleb Friedman
Keywords(s): Chemistry, Energy, Environment, Featured, Materials & Chemicals, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Automated EXAFS Spectra Interpretation
050-9531 System and Method for Automated EXAFS Spectra Interpretation via Neural Network-Driven Data Pipeline
High-throughput catalyst characterization and testing using neural network-driven data pipeline
Background:
Extended X-ray absorption fine structure (EXAFS) spectroscopy is a critical technique for determining the local atomic structure...
Published: 3/4/2026
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Inventor(s): Anatoly Frenkel, Nicholas Marcella, Ryuichi Shimogawa
Keywords(s):
Category(s): Technology Classifications > Information Technology, Technology Classifications > Nanotechnology, Technology Classifications > Research Tools and Reagents, Campus > Stony Brook University
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Deuterium and Fluorine-18 Labeled Glutamine – a PET Imaging Agent with Enhanced in Vivo Stability
050- 9471 Deuterium and Fluorine-18 Labeled Glutamine – a PET Imaging Agent with Enhanced in Vivo Stability
This technology offers a powerful tool for elucidating in vivo glutamine metabolism with enhanced image clarity for cancer diagnosis
Background:
Accurate and comprehensive non-invasive imaging of cancer metabolism is crucial for diagnosis...
Published: 2/10/2026
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Inventor(s): Wenchao Qu, Bao Hu, Hari Akula, Paul Vaska
Keywords(s):
Category(s): Technology Classifications > Medical Imaging, Technology Classifications > Nanotechnology, Technology Classifications > Research Tools and Reagents, Campus, Campus > Stony Brook University
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Method to Determine Quality of Mitochondrial Cargo in Extracellular Vesicles
A novel method that measures mitochondrial membrane potential in extracellular vesicles, providing a direct readout of mitochondrial quality and utility.
Background:
Studies have shown that EV-mediated intercellular communication is influenced, at least in part, by the mitochondrial cargo contained within EVs. This highlights the importance of rigorous...
Published: 2/19/2026
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Inventor(s): Barbara Alevriadou, Zahid Manzar, Hans Minderman
Keywords(s): Biotechnology, Diagnostic, Healthcare, Pharmaceutical, Research Tool, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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Enhanced Fluorophore Discrimination in Fluorescence Microscopy Using Multi View Spectral Unmixing with Photobleaching Dynamics
This technology allows researchers to more easily distinguish hundreds of fluorescent labels in a single image, useful for a wide variety of biological applications.
Background:
There are hundreds to thousands of different cells or other structures that can be labeled with fluorescent reporters in a biological sample, and then imaged on a fluorescence...
Published: 3/26/2026
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Inventor(s): Alex Valm, Yunlong Feng, Ruogu Wang
Keywords(s): fluorescence, fluoroscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Bioinformatics, Technology Classifications > Artificial Intelligence, Technology Classifications > Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays, Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Dental
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RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes.
Background:
Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 3/20/2026
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Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses
This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases.
Background:
In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 10/29/2025
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Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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