Development of Lectins with Protein Engineering
Lectins that exclusively bind sialylated core-2 O-linked glycans within cancerous tissue with a higher affinity than physiologically healthy tissue.
Background:
Lectins bind complex carbohydrates on cell surfaces and secreted glycoproteins. These carbohydrates are modified during disease from altered metabolism, though the proteins themselves are...
Published: 11/20/2024
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Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
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RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes.
Background:
Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 10/3/2024
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Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
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In Vitro Dental Plaque Culture Model for Biofilm Structural Analyses
This technology provides a valuable tool for studying the molecular and cellular basis of dental plaque-mediated diseases.
Background:
In vitro oral microcosm communities, seeded with mixed communities of human dental plaque, have proven to be essential tools for studying the taxonomic composition of dental plaque communities and changes in community...
Published: 10/3/2024
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Inventor(s): Alex Valm
Keywords(s): biofilm control, dental, dental materials, structural biology, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental, Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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NRN-EZ: An application to streamline biophysical modeling of synaptic integration using NEURON
NRN-EZ is an interactive application that allows NEURON users without extensive programming experience to define complex patterns of synaptic input activation.
Background:
Modeling software programs such as NEURON are widely used in the neuroscience community to address a broad range of research questions, including how neurons integrate synaptic...
Published: 9/26/2024
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Inventor(s): Annalisa Scimemi, Evan Cobb
Keywords(s): neuron, software, synapic integration, synapse, Technologies
Category(s): Technology Classifications > Information Technology, Campus > University at Albany, Technology Classifications > Education and Training, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biomedical Science and Engineering
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Continuous Ammonia Production from Air
An integrated system with a cascading plasma electrochemical process to generate ammonia at room temperature and pressure, using water as the proton source, significantly lowering the carbon footprint while providing the highest ammonia production rate among the reported literature.
Background:
Ammona synthesis is a fundamental reaction for the production...
Published: 9/14/2024
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Inventor(s): Yuguang Li, Xiaoli Ge
Keywords(s): Chemistry, Energy, Environment, Featured, Instrumentation, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Clean Energy, Technology Classifications > Engineering, Technology Classifications > Energy, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Research Tools and Reagents
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Modified Graphene Oxide-based Membranes for Mixture Separations
A facile method for developing membranes for hydrocarbon mixture separations by depositing graphene oxide flakes on a commercial porous substrate.
Background:
Molecular separations in mixtures account for approximately 50% of industrial energy use in the US alone, so there is high demand for alternate separation technologies, particularly for liquid...
Published: 4/10/2024
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Inventor(s): Miao Yu, Bratin Sengupta
Keywords(s): Chemistry, Featured, Materials & Chemicals, Research Tool, Surface Research, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Identifying Wood Species from Chemical Signature
Quickly identifies wood species, both in the form of a log or as a product made from wood.
Background:
Currently, there are very strict national and international laws governing the buying and selling of wood and wood-based products. These laws are designed to curtail illegal trade in endangered tree species. However, it can be exceedingly difficult...
Published: 9/19/2024
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Inventor(s): Rabi Musah
Keywords(s): chemistry, forensics, statistical analysis, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
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Positron Emission Tomography (PET) Radiotracer
Composition, method and diagnostic use of positron imaging tomography imaging agent for bacterial infection detectionRSS.HDBackground> Background: <Positron emission tomography (PET) radiotracer is a diagnostic tool to detect bacterial infection in humans. A deficiency exists in clinical diagnostic tools capable of identifying bacterial infections...
Published: 2/1/2024
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Inventor(s): Peter Tonge, Yong Li, Fereidoon Daryaee, Peter Smith-Jones, Labros Meimetis
Keywords(s):
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Campus, Campus > Stony Brook University
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M-Track: A New Software to Track Mouse Grooming
A software toolkit that automates the tracking of fine detail movements during rodent grooming episodes. Background: Grooming is a complex and robust innate behavior, commonly performed by most vertebrate species. For example, rodent grooming consists of a series of stereotyped patterned strokes, the frequency and duration of which are affected by...
Published: 1/24/2024
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Inventor(s): Annalisa Scimemi, Sheldon Reeves
Keywords(s):
Category(s): Technology Classifications > Research Tools and Reagents, Campus > University at Albany
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Laser Ablation Direct Analysis in Real Time-Imaging Mass Spectrometry (LADI-MS)
Offers the potential of real-time small-sample analysis for a very large variety of applications.
Background:
Real Time Imaging Mass Spectrometry (RTMS) is a method for analyzing and identifying biological samples in real time. RTMS can be used in an extremely broad variety of applications, involving chemistry, biochemistry, food sciences, and medicine....
Published: 1/23/2024
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Inventor(s): Rabi Musah
Keywords(s): analytical chemistry, Biomarker discovery, chemistry, forensic testing, image acquisition, imaging, life sciences, Mass spectrometry imaging, medical imaging, Natural products, Phytochemistry, Small-molecule profiling, Small-molecule spatial distribution mapping, Species discrimination, Species identification, Technologies, Tissue analysis, wood anatomy, wood science
Category(s): Campus > University at Albany, Technology Classifications > Agriculture, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Environment, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents
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